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Die molekulare Basis von Gesundheit: Wie Epigenetik und Ernährung unser Leben beeinflussen
Par Carsten Carlberg. 2023
Lernen Sie, wie Sie durch die wissenschaftlichen Erkenntnisse der Selbstheilung und der Wechselwirkung zwischen Ernährung und Genom Ihre Gesundheit positiv…
beeinflussen können. Tauchen Sie ein in die Welt der Epigenetik, die Ihnen erklärt, wie Sie Ihre Gesundheit fördern und das Beste aus sich selbst herausholen können.Zunächst führt Sie das Werk in die molekularen Grundlagen ein, wie jede einzelne Zelle funktioniert und Information über ihre Umgebung verarbeitet. Letzteres hat sehr viel mit Epigenetik zu tun, die ein zentrales Thema in diesem Buch ist. Die Epigenetik, die für die Identität der mehr als 400 verschiedenen Zelltypen unseres Körpers entscheidend ist, hat auch einen dynamischen Aspekt. Sie lernen, wie intrazellulärer Signalübertragungswege über extrazelluläre Signale aktiviert werden und damit Transkriptionsfaktoren und Chromatin-modifizierenden Enzymen beeinflussen. Viele dieser Signale stammen direkt oder indirekt von unserer Ernährung. Letztere ist das wichtigste externe Signal, dem wir täglich ausgesetzt sind. Das führt zum zweiten zentralen Thema dieses Buches, der Nutrigenomik. Die Nahrung, die wir täglich zu uns nehmen, ist weit mehr als eine Ansammlung von Kohlenhydraten, Proteinen, Lipiden, Vitaminen und Mineralien, die Energie und Bausteine für unseren Körper liefert. Das faszinierende Fachgebiet der Nutrigenomik beschreibt die Wechselwirkung zwischen Nahrungsmolekülen, ihren Metaboliten und unserem (Epi)genom. Viele Nahrungsbestandteile, wie beispielsweise ungesättigte Fettsäuren, aktivieren direkt Transkriptionsfaktoren oder verursachen Veränderungen in den Konzentrationen von Metaboliten. Diese beeinflussen wiederum die Aktivität von Chromatin-modifizierenden Enzymen. Auf diese Weise „sprechen“ Moleküle unseres Frühstücks, Mittagessen oder Abendessen mit unserem Genom bzw. Epigenom.Tauchen Sie ein in die faszinierende Welt der Selbstheilung und Verantwortung für Ihre Gesundheit!Arab Americans in the United States: Immigration, Culture and Health (International Perspectives on Migration)
Par Shaikha H. Al-Kuwari. 2024
This open access book provides a unique perspective on the relationship between immigration, culture, and health. It presents a cross-cultural…
perspective between culture and illness. It touches upon identity struggles, the notion of not feeling “safe, understood, accepted,” and its relation to Arab American health. The book provides a comprehensive review of the history of Muslims in America and discusses better healthcare services for chronic illness—diabetes. It provides an ethnographic framework for building cultural belief models of illness, which helps study any illness among any population. It is a must-read for everyone interested in understanding the relationship among culture, health, and immigration, as well as the importance of building cultural belief models of illness and their possible impact on providing better healthcare services. The book is of interest to scholars, caregivers, and those living with diabetes.Handbuch Digitale Gesundheitswirtschaft: Analysen und Fallbeispiele
Par Sabine Bohnet-Joschko, Katharina Pilgrim. 2023
Das Handbuch digitale Gesundheitswirtschaft liefert eine qualitätsgeprüfte umfassende Übersicht zu Chancen und Herausforderungen der digitalen Transformation des Gesundheitswesens. Dabei werden…
Technologien, regulatorischer Rahmen, innovative Geschäftsmodelle und Einsatzbereiche jeweils mit branchenrelevanten Fallbeispielen ergänzt. Sowohl ökonomische als auch versorgungsrelevante Aspekte werden diskutiert - anhand aktueller wissenschaftlicher internationaler Studien.Essential Herbs: Treat Yourself Naturally with Herbs and Homemade Remedies
Par Neal'S Yard Remedies. 2020
Find your route to natural wellness with Neal's Yard Remedies' expert guide to using medicinal herbs.Essential Herbs offers expert advice…
and know-how you can trust in this detailed guide, which features an illustrated directory of 100 key herbs, including hemp, lavender, thyme, aloe vera, and lemongrass. Discover the treatment potential for each plant, and how you can prepare and use them to best effect.Alongside the directory, the book features more than 70 recipes designed to heal the body from the inside out, all of which can be prepared in your own kitchen. Try a fennel and chamomile tea to aid digestion, a cranberry and apricot power bar to boost energy levels, or a beeswax and calendula balm to combat stretch marks.With this easy-to-use treatment guides to help you find the herbs you need at a glance, Essential Herbs is a comprehensive guide to staying healthy the natural way.John Loeser: The Man Who Reimagined Pain
Par Jane C. Ballantyne. 2023
This uniquely written title presents both the fascinating biography of Dr. John Loeser, a visionary pioneer in the field of…
pain medicine, as well as the compelling account of the birth and evolution of pain medicine in the United States and beyond. In this captivating work, readers are taken down the path of an extraordinary man who not only shaped the discipline of pain medicine but also embraced a multitude of passions, leaving an indelible mark on those lucky enough to know him. Prior to the pivotal role Loeser played in helping pain medicine emerge as a recognized field in the 1980s, he had already established himself as a highly respected neurosurgeon and co-author of a definitive text on neuroembryology. However, when he became immersed in the world of pain medicine, an entirely new frontier beckoned—one that held the promise of reducing human suffering and revolutionizing the way we understand and manage pain. Soon Loeser was deeply engaged in pain research and clinical practice and was advocating for better diagnostics, cutting-edge technologies, and a deeper understanding of pain mechanisms. Loeser not only played a leading role in the evolution of pain medicine in the 1980s but became the chief architect and champion of multidisciplinary pain management. Indeed, this outstanding biography amounts to two absorbing stories in one – the exceptional life of Loeser, complete with engrossing details of his early-life background, along with an absorbing history of the modern pain management movement. A colleague of Loeser for many years, the author skillfully and colorfully details the major, and often intimate, landscape of people, friendships, anecdotes, episodes, and ideas that weave into a rich context for understanding a multi-talented man who was not only a fighter for his beliefs and a major leader among all pain management professionals and organizations, but was also equally at home in his command of the operating room and in carving wooden masks based on northwestern indigenous traditions. An invaluable contribution to the literature, John Loeser: The Man Who Reimagined Pain will be of great interest to physicians and clinicians in every field, as well as to laypersons interested in the incomparable story of a man who accomplished so much and means so much to family, friends, and colleagues around the world.Advanced Robotic Spine Surgery: A case-based approach
Par Michael Y. Wang, Steele III, William J., Timur Urakov. 2021
Robotic spine surgery is one of the fastest growing segments of the spine surgery market. Surgeons specialising in spine surgery…
are highly motivated to learn and improve their understanding of the indications,application,and future clinical scope of using new technological platforms. Spinal surgeons face time pressures but are hungry for new ways to effectively treat patients. This book presents information in the case study format. By using examples of surgical cases of an advanced nature (e.g. spinal deformity, minimally invasive surgery, combinatorial technology using the robot) this will differ from other texts. Each case study is written by a well-respected expert in the field and represents that surgeon’s most monumental case. Each case contains a concise patient history with indications, contraindications and insights to help the reader assimilate expert knowledge. The case studies examine both the unique and technical aspects of robotic planning and surgical execution, and include seminal bullet point sections: Key take away points; Tips and pearls to avoid pitfalls; and "how I could have done this better.” This new text provides valuable and practical knowledge for spine surgeons and others involved in robotic surgery.Rote Augen, Grauer Star, Kranke Makula: Augenkrankheiten vorbeugen – Die richtige Therapie
Par Birgit Hartmann, Wolfram Goertz. 2023
Ratgeber, Augenbeschwerden kennen, vorbeugen und behandelnSie sehen verzerrt, haben juckende Augen oder Diabetes? Dieser bewährte Ratgeber gibt einen hervorragenden Überblick…
über die häufigsten Augenleiden und Behandlungsansätze.Rote Augen, Grauer und Grüner Star, Erkrankungen an der Makula und durch Diabetes hervorgerufene Netzhautschäden gehören zu den häufigsten Ursachen für eine starke Sehminderung und Blindheit. Für die Erhaltung des Sehvermögens ist die Früherkennung entscheidend. Denn es gilt: Je eher eine Erkrankung festgestellt wird, desto früher kann man mit einer notwendigen Behandlung beginnen - und umso besser ist der Krankheitsverlauf. Verständlich und kurz & knapp werden die einzelnen Erkrankungen, mögl. Symptome und Ursachen sowie Behandlungsmöglichkeiten erklärt. Auch die Fragen, wie kann man der Entstehung von Augenkrankheiten vorbeugen und welche Vorsorgeuntersuchungen (IGeL) sind sinnvoll, werden von den Experten erläutert. Das Buch geht auf Besonderheiten bei Kindern und älteren Menschen ein und beleuchtet auch das Thema Kontaktlinsen und Lasern bei Fehlsichtigkeit. Ein empfehlenswerter Patientenratgeber zum Nachlesen und fürs Wartezimmer !You Are You and You Are Great
Par Melissa Marie. 2024
Many of us have a loved one who has Autism Spectrum. This can be a difficult discussion to have with…
children in our lives especially if they require the help of many people. You Are You and You Are Great was written to help illustrate that, no matter what, we are all in this together, and we are all here to help. This book should help promote acceptance and is meant to show children on and off the spectrum that we are all human, but that our differences make us special. This is the perfect book for families, schools, and libraries to facilitate conversations about inclusion and community building.A Voice from Old New York: A Memoir of My Youth
Par Louis Auchincloss. 2010
An &“entertaining and occasionally even moving&” personal recollection by the lawyer, historian, and renowned chronicler of old-money WASP society (The…
Boston Globe). At the time of his death, Louis Auchincloss—enemy of bores, self-pity, and stale gossip—had just finished taking on a subject he had long avoided: himself. His memoir confirms that, despite the spark of his fiction, Auchincloss himself was the most entertaining character he ever created. No traitor to his class, but occasionally its critic, Auchincloss returns to his insular society, which he maintains was less interesting than its members admitted—and unfurls his life with dignity, summoning family (particularly his father, who suffered from depression and forgave him for hating sports) and intimates. Brooke Astor and her circle are here, along with glimpses of Jacqueline Onassis. Most memorable, though, is Auchincloss&’s way with those outside the salon: the cranky maid; the maiden aunt, perpetually out of place; the less-than-well-born boy who threw himself from a window over a woman and a man. Above all, here is what it was like to be Auchincloss, an American master, a New York Times–bestselling novelist, and a rare, generous, lively spirit to the end. &“[Auchincloss] concentrates on bringing back to life—literary alchemy, after all—the people who loved him: his mother, father, aunts, uncles, school friends and colleagues. He understands how lucky he was to have them, and &‘A Voice From Old New York&’ is his thank-you note.&” —The New York TimesMacrolides as Immunomodulatory Agents (Progress in Inflammation Research #92)
Par Bruce K. Rubin, Masaharu Shinkai. 2024
For over 50 years, clinicians have known that macrolide antibiotics have effects on inflammation and the immune system that are…
not related to their antimicrobial properties. These immunomodulatory properties, best described for treating inflammatory airway diseases, protect the lung and the host and improve clinical status. This book summarizes our current knowledge regarding proposed mechanisms for these properties, established clinical results, and what the future may hold with emphasis on novel clinical applications and the fascinating development of non-antimicrobial macrolides with preserved and enhanced immunomodulatory properties.Breast Cancer Research and Treatment: Innovative Concepts (Cancer Treatment and Research #188)
Par Ouissam Al Jarroudi, Khalid El Bairi, Giuseppe Curigliano. 2023
This book focuses on innovative treatment options for breast cancer, including surgery, radiotherapy, systemic therapy and of course immunotherapy that…
is changing outcomes in some aggressive breast cancer histotypes. Subsequent chapters also address the ongoing emerging research in the screening, diagnostics, and management of all subtypes of breast cancers. All current landscapes and future perspectives in each molecular subtype: luminal, HER2-positive, and triple-negative breast cancers are discussed within the different chapters.Breast cancer is still the most common cancer and cause of cancer deaths among women worldwide. The improvement of breast cancer outcome appears to be strictly related to the validation of precise biomarkers that enable us to better select personalized approaches in breast cancer management.The closing chapters deal with the challenges of conducting research in the era of precision medicine for cancer. The book is edited and authored by leading experts in this field and will be of interest for clinicians and scientists alike.Medicinal Plants and Antimicrobial Therapies
Par Vinay Kumar, Varsha Shriram, Abhijit Dey. 2024
This book serves as an excellent comprehensive material covering the current understandings and updates on antimicrobial resistance (AMR) and the…
use of medicinal plant resources for tackling it. Chapters cover important aspects of AMR and strategies to address this threatening issue with medicinal plants and their resources. One health perspectives for addressing AMR have been presented for the readers. Antimicrobial medicinal plant therapeutic resources including crude extracts, active fractions, pure molecules and essential oils, besides using them as functionalizing agents for nano-antimicrobials have been covered. Further, plant endophytes as a source of antimicrobial compounds have been discussed. Chapters cover both the bactericidal as well as resistance-reversal (or potentiating/ combinatorial therapies) potencies of medicinal plant resources. The book also focuses on how medicinal plant resources effectively target major determinants of AMR. Use of metabolomics in understanding and targeting AMR mechanisms and identifying potent phyto-therapeutics has been discussed as well. The book is a valuable read for both experienced and younger researchers working in the field of AMR and related fields in biomedicine, pharmacy, and clinical research.Univentricular Congenital Heart Defects and the Fontan Circulation: Practical Manual for Patient Management
Par Paul Clift, Konstantinos Dimopoulos, Annalisa Angelini. 2023
This book provides a concise, practically applicable guide to the management of patients born with a univentricular heart defect. It…
describes the anatomy and epidemiology of the univentricular heart, while guidance is provided on how to manage both fetal and neonatal patients with this defect, as well as those in later childhood and adulthood. The utilization of the Fontan operation for patients with a univentricular heart is described in detail. Management of early and late Fontan failure is also discussed, and the pregnant patient is also described, enabling the reader to develop a deep understanding of how to manage these patients in their daily practice. Univentricular Congenital Heart Defects: Practical Manual for Patient Management comprehensively reviews the management of univentricular heart defects and the use of Fontan-type surgery. It is a valuable resource for the experienced practitioner seeking a manual on the latest available techniques and for trainees who want to develop a thorough understanding of how to manage patients with these congenital heart defects.Handbook of Cerebrovascular Disease and Neurointerventional Technique (Contemporary Medical Imaging)
Par Mark R. Harrigan, John P. Deveikis. 2023
This fourth edition offers a practical guide to endovascular treatment of cerebrovascular disease and provides a comprehensive reference for the…
related neurovascular anatomy and the various disorders that affect the vascular system. Chapters cover fundamental principles underlying cerebral and spinal angiography; interventional techniques, devices, and practice guidelines; and commonly encountered cerebrovascular disorders for which interventional and endovascular methods are appropriateBuilding on the previous edition, the text is presented similarly in style and scope to emphasize accessibility and ease of reading. All chapters are fully updated to include more recent data, and obsolete products and techniques are replaced with the most current technology. Some key updates include:A greater emphasis on the use of radial artery access for the discussed endovascular techniques.The associations of COVID-19 with ischemic stroke and the implications of providing care for cerebrovascular patients during a pandemic.An extensive update to the acute ischemic stroke chapter with new references and format to more closely follow the format of other chapters in that section.Expansion of the pediatric sections of disease chapters, including discussions of genetic associations with disease. This is an ideal guide for clinicians and trainees in neurology, neurosurgery and neuroradiology, as well as practicing clinicians in related fields caring for patients with cerebrovascular disease.Blockchain in Healthcare: Analysis, Design and Implementation (Future of Business and Finance)
Par Chang Lu, Mohan Tanniru. 2023
This books brings readers a holistic understanding of blockchain adoption in healthcare by not only considering the technical fundamentals of…
use cases, but also the regulatory, informational and organizational challenges and solutions. The book also provides frameworks and toolkits to manage the entire life cycle of adoption, including analysing the environment and feasibility, application design from a user-centred perspective, and implementation strategies that would overcome organizational and informational barriers. Specific issues addressed include but are not limited to: How to analyse the value propositions in healthcare and which distributed actors should be engaged to fulfil these propositions? What policies and practices need to be reviewed to ensure security and privacy of the information shared? How to design blockchain systems that seamlessly integrate with other stakeholder applications, while only the needed information is in the distributed architecture? How can blockchain implementation be managed from governance and risk mitigation perspectives, especially when multiple actors are involved?By reading this book, blockchain enthusiasts, health informatics professionals and healthcare executives will be better prepared to leverage the transformative potential of blockchain for healthcare.Medical Decision Making
Par Harold C. Sox, Michael C. Higgins, Douglas K. Owens, Gillian Sanders Schmidler. 2024
MEDICAL DECISION MAKING Detailed resource showing how to best make medical decisions while incorporating clinical practice guidelines and decision support…
systems Sir William Osler, a legendary physician of an earlier era, once said, “Medicine is a science of uncertainty and an art of probability.” In Osler’s day, and now, decisions about treatment often cannot wait until the diagnosis is certain. Medical Decision Making is about how to make the best possible decision given that uncertainty. The book shows how to tailor decisions under uncertainty to achieve the best outcome based on published evidence, features of a patient’s illness, and the patient’s preferences. Medical Decision Making describes a powerful framework for helping clinicians and their patients reach decisions that lead to outcomes that the patient prefers. That framework contains the key principles of patient-centered decision-making in clinical practice. Since the first edition of Medical Decision Making in 1988, the authors have focused on explaining key concepts and illustrating them with clinical examples. For the Third Edition, every chapter has been revised and updated. Written by four distinguished and highly qualified authors, Medical Decision Making includes information on: How to consider the possible causes of a patient’s illness and decide on the probability of the most important diagnoses. How to measure the accuracy of a diagnostic test. How to help patients express their concerns about the risks that they face and how an illness may affect their lives. How to describe uncertainty about how an illness may change over time. How to construct and analyze decision trees. How to identify the threshold for doing a test or starting treatment How to apply these concepts to the design of practice guidelines and medical policy making. Medical Decision Making is a valuable resource for clinicians, medical trainees, and students of decision analysis who wish to fully understand and apply the principles of decision making to clinical practice.ACSM's Resources for the Group Exercise Instructor
Par American College of Sports Medicine. 2023
ACSM’s Resources for the Group Exercise Instructor, 2nd Edition, equips fitness professionals with the knowledge and the skills needed to…
effectively lead group exercise in gyms, studios, recreational facilities, and clubs. An essential resource for undergraduate exercise science programs, students in pre-professional programs, and those independently prepping for the ACSM-GEI certification, this engaging, accessible text reflects the authoritative expertise of the American College of Sports Medicine (ACSM) and delivers complete preparation for becoming an ACSM Certified Group Exercise Instructor. The extensively revised and reorganized 2nd Edition streamlines learning and aligns content to the domains of the ACSM Certified Group Exercise Instructor Exam, boosting exam confidence and delivering step-by-step guidance to ensure success in professional practice.Coming Out as Dalit: A Memoir of Surviving India's Caste System
Par Yashica Dutt. 2024
&“…a moving personal story and a useful educational examination of persistent discrimination&”—Kirkus ReviewsFor readers of Caste, the coming-of-age story of…
a Dalit individual that illuminates systemic injustice in India and its growing impact on US society Winner of the Sahitya Akademi Yuva Puruskar, 2020Born into a "formerly untouchable manual-scavenging family in small-town India," Yashica Dutt was taught from a young age to not appear &“Dalit looking.&” Although prejudice against Dalits, who compose 25% of the population, has been illegal since 1950, caste-ism in India is alive and well. Blending her personal history with extensive research and reporting, Dutt provides an incriminating analysis of caste&’s influence in India over everything from entertainment to judicial systems and how this discrimination has carried over to US institutions.Dutt traces how colonial British forces exploited and perpetuated a centuries old caste system, how Gandhi could have been more forceful in combatting prejudice, and the role played by Dr. B. R. Ambedkar, whom Isabel Wilkerson called &“the MLK of India&’s caste issues&” in her book Caste. Alongside her analysis, Dutt interweaves personal stories of learning to speak without a regional accent growing up and desperately using medicinal packs to try to lighten her skin.Published in India in 2019 to acclaim, this expanded edition includes two new chapters covering how the caste system traveled to the US, its history here, and the continuation of bias by South Asian communities in professional sectors. Amid growing conversations about caste discrimination prompting US institutions including Harvard University, Brandeis University, the University of California system, and the NAACP to add caste as a protected category to their policies, Dutt&’s work sheds essential light on the significant influence caste-ism has across many aspects of US society.Raw and affecting, Coming Out as Dalit brings a new audience of readers into a crucial conversation about embracing Dalit identity, offering a way to change the way people think about caste in their own communities and beyond.Toxicology of Fishes
Par Kristine L. Willett, Neelakanteswar Aluru. 2024
This up-to-date, comprehensive toxicology handbook is devoted to the effects of environmental pollution on fish. Fish species represent nearly half…
of all vertebrates and have become important sentinels for environmental contamination and model organisms for understanding adverse outcomes from exposures. This new edition is written by recognized experts, and it highlights the significant research progress in fish toxicology that has resulted from rapid technological developments in analytical, biochemical, and genomic sciences. The book: Discusses fundamental topics such as toxicokinetics in fishes, processes governing biotransformation within these organisms, and reactive oxygen species and oxidative stress. Explains key target organ systems for chemical impacts in fish, such as the nervous and immune systems, and how fishes can develop resistance to chemical toxicity. Covers multi-transgenerational effects on fishes, epigenetics, proteomics and metabolomics, and adverse outcome pathways. Replacing the case studies in the first edition, this update delves into the impacts of microplastics, pharmaceuticals, and oil spills in dedicated final chapters. With nearly 200 illustrations and tables, this comprehensive reference work presents concepts in a way that is useful for both novices to and experts in the field of fish toxicology.The Future of Alzheimer's: Finding Inspiration & Hope Through Expert Insight
Par Sharon Ricardi. 2023
A collection of informative and inspirational thoughts of many of the nation&’s leaders in research, medicine, education, senior care and…
advocacy around the subject of Alzheimer&’s disease.The Future of Alzheimer's features candid views from experts on how they respond today to someone on the difficult journey of Alzheimer&’s and what they believe is the future hope for a cure.More than 20 experts in the field of Alzheimer's research or caretakers are asked two key questions:What advice would you give to the loved ones of someone who is newly diagnosed?Do you think there will be a cure, and if so, when?Their answers help provide context and hope for patients, caretakers and loved ones looking for answers by providing helpful insights on the disease and what's to come.Alzheimer's prevalence in the US makes it the 6th leading cause of death, killing more than half a million people, mainly seniors, every year and experts believe this number will only grow. The Future of Alzheimer's seeks to make this and other forms of dementia less of the devastating diagnosis it is now for all of those people.