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Toxicology of Fishes
Par Kristine L. Willett, Neelakanteswar Aluru. 2024
This up-to-date, comprehensive toxicology handbook is devoted to the effects of environmental pollution on fish. Fish species represent nearly half…
of all vertebrates and have become important sentinels for environmental contamination and model organisms for understanding adverse outcomes from exposures. This new edition is written by recognized experts, and it highlights the significant research progress in fish toxicology that has resulted from rapid technological developments in analytical, biochemical, and genomic sciences. The book: Discusses fundamental topics such as toxicokinetics in fishes, processes governing biotransformation within these organisms, and reactive oxygen species and oxidative stress. Explains key target organ systems for chemical impacts in fish, such as the nervous and immune systems, and how fishes can develop resistance to chemical toxicity. Covers multi-transgenerational effects on fishes, epigenetics, proteomics and metabolomics, and adverse outcome pathways. Replacing the case studies in the first edition, this update delves into the impacts of microplastics, pharmaceuticals, and oil spills in dedicated final chapters. With nearly 200 illustrations and tables, this comprehensive reference work presents concepts in a way that is useful for both novices to and experts in the field of fish toxicology.The Future of Alzheimer's: Finding Inspiration & Hope Through Expert Insight
Par Sharon Ricardi. 2023
A collection of informative and inspirational thoughts of many of the nation&’s leaders in research, medicine, education, senior care and…
advocacy around the subject of Alzheimer&’s disease.The Future of Alzheimer's features candid views from experts on how they respond today to someone on the difficult journey of Alzheimer&’s and what they believe is the future hope for a cure.More than 20 experts in the field of Alzheimer's research or caretakers are asked two key questions:What advice would you give to the loved ones of someone who is newly diagnosed?Do you think there will be a cure, and if so, when?Their answers help provide context and hope for patients, caretakers and loved ones looking for answers by providing helpful insights on the disease and what's to come.Alzheimer's prevalence in the US makes it the 6th leading cause of death, killing more than half a million people, mainly seniors, every year and experts believe this number will only grow. The Future of Alzheimer's seeks to make this and other forms of dementia less of the devastating diagnosis it is now for all of those people.An evidence-based guide for doctors diagnosing, testing, and treating children with PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Strep infections).In…
the early 1990s, a group of researchers at the National Institute of Mental Health began collecting data on children who had developed neuropsychiatric disorders (OCD and tics) following infections. They found evidence that antineuronal antibodies had developed in some of these children which attacked the basal ganglia region of the brain. MRI and PET scans in these children demonstrated inflammatory changes in the basal ganglia as well. In 1997, the researchers published the first article to describe this syndrome that they named PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Strep infections). In PANDAS, an autoimmune attack on the brain occurs following a Strep infection. PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) is a broader term that also includes cases following exposure to other infections, toxins, and even stress. Clinicians treating children with PANS and PANDAS have found that antibiotics targeted at the offending organisms, steroids, and IVIG results in marked improvement and occasionally complete remission of the neuropsychiatric symptoms. Disturbing symptoms consistent with many DSM-5 psychiatric disorders manifest in patients with PANS and PANDAS—yet we know that there is a biologic basis for the changes in these children. As a result, these disorders require us, as physicians, to view mental illness in an entirely new way. Resistance to this change in paradigm has made PANS and PANDAS difficult for clinicians to diagnose, unbearable for parents to endure, and controversial for scholars to accept. As such, there is no recognized standard of care. We have written this work in an effort to change that. This is a textbook by physicians for physicians. It was written to bring back some of the art of medicine to physicians caring for a group of children and families who really need it. PANS and PANDAS are complex disorders that demand a rich, multifaceted response with novel treatment approaches. The material in this book is assembled from the peer-reviewed medical literature, in combination with over thirty years of clinical experience caring for the sickest patients, both in and out of the hospital. Here you will find conclusive evidence for the existence and pathophysiology of PANS and PANDAS, alongside testing and treatment interventions the author has successfully used in his own practice with hundreds of children. The book concludes with rich appendices including commonly used labs, doses of medications and supplements, a sample flare protocol, extensive support for parents, sample IVIG orders, and much more. We hope this resource allows you, the physician, to help these suffering families heal.Cancer screening has been carried out for six decades – however, there are many unsolved problems: how to estimate key parameters…
involved in screenings, such as sensitivity, the time duration in the preclinical state (i.e., sojourn time), and time duration in the disease-free state; how to estimate the distribution of lead time, the diagnosis time advanced by screening; how to evaluate the long-term outcomes of screening, including the probability of overdiagnosis among the screen-detected; when to schedule the first exam based on one’s current age and risk tolerance; and when to schedule the upcoming exam based on one’s screening history, age, and risk tolerance. These problems need proper probability models and statistical methods in order to be dealt with. Features: This book gives a concise account of the analysis of cancer screening data, using probability models and statistical methods. Real data sets are provided so that cancer researchers and statisticians can apply the methods in the learning process. It develops statistical methods in the commonly used disease progressive model. It provides solutions to practical problems and introduces open problems. It provides a framework for the most recent developments based on the author’s research. The book is primarily aimed at researchers and practitioners from biostatistics and cancer research. Readers should have the prerequisite knowledge of calculus, probability, and statistical inference. The book could be used as a one-semester textbook on the topic of cancer screening methodology for a graduate-level course.Actinomycetes in Marine and Extreme Environments: Unexhausted Sources for Microbial Biotechnology
Par D. İpek Kurtböke. 2021
The discovery and development of antibiotics has been one of the most significant advances in medicine. In a golden era…
lasting from the 1940s to the late 1960s, antibiotic research provided mankind with a wide range of structurally diverse and effective agents for the treatment of microbial infections. Since then, actinomycetes, most notably members of the genus Streptomyces, have uninterruptedly proved to be a particularly rich source of antibiotics and other therapeutic and biotechnologically important compounds. This book brings together expert actinomycetologists to communicate the importance of finding novel antibiotic producing actinomycetes in extreme and marine environments in the light of molecular advances.Moses and the Monster and Miss Anne
Par Carole C. Marks. 2008
This engaging history presents the extraordinary lives of Patty Cannon, Anna Ella Carroll, and Harriet Tubman, three "dangerous" women who…
grew up in early-nineteenth-century Maryland and were vigorously enmeshed in the social and political maelstrom of antebellum America. The "monstrous" Patty Cannon was a reputed thief, murderer, and leader of a ruthless gang who kidnapped free blacks and sold them back into slavery, whereas Miss Anna Ella Carroll, a relatively genteel unmarried slaveholder, foisted herself into state and national politics by exerting influence on legislators and conspiring with Governor Thomas Holliday Hicks to keep Maryland in the Union when many state legislators clamored to join the Confederacy. And, of course, Harriet Tubman--slave rescuer, abolitionist, and later women's suffragist--was both hailed as "the Moses of her people" and hunted as an outlaw with a price on her head worth at least ten thousand dollars. All three women lived for a time in close proximity on the Eastern Shore of Maryland, an isolated region that thrived on tobacco and then lost it, procured slaves and then lost them, and produced strong-minded women and then condemned them. Though they never actually met, and their backgrounds and beliefs differed drastically, these women's lives converged through their active experiences of the conflict over slavery in Maryland and beyond, the uncertainties of economic transformation, the struggles in the legal foundation of slavery and, most of all, the growing dispute in gender relations in America. Throughout this book, Carole C. Marks gleans historical fact and sociological insight from the persistent myths and exaggerations that color the women's legacies, and she investigates the common roots and motivations of three remarkable figures who bucked the era's expectations for women. She also considers how each woman's public identity reflected changing ideas of domesticity and the public sphere, spirituality, and legal rights and limitations. Cannon, Carroll, and Tubman, each in her own way, passionately fought for the future of Maryland and the United States, and from these unique vantage points, Moses and the Monster and Miss Anne portrays the intersecting and conflicting forces of race, economics, and gender that threatened to rend a nation apart.Image synthesis across and within medical imaging modalities is an active area of research with broad applications in radiology and…
radiation oncology. This book covers the principles and methods of medical image synthesis, along with state-of-the-art research. First, various traditional non-learning-based, traditional machine-learning-based, and recent deep-learning-based medical image synthesis methods are reviewed. Second, specific applications of different inter- and intra-modality image synthesis tasks and of synthetic image-aided segmentation and registration are introduced and summarized, listing and highlighting the proposed methods, study designs, and reported performances with the related clinical applications of representative studies. Third, the clinical usages of medical image synthesis, such as treatment planning and image-guided adaptive radiotherapy, are discussed. Last, the limitations and current challenges of various medical synthesis applications are explored, along with future trends and potential solutions to solve these difficulties. The benefits of medical image synthesis have sparked growing interest in a number of advanced clinical applications, such as magnetic resonance imaging (MRI)-only radiation therapy treatment planning and positron emission tomography (PET)/MRI scanning. This book will be a comprehensive and exciting resource for undergraduates, graduates, researchers, and practitioners.Ralph Johnson Bunche: Public Intellectual and Nobel Peace Laureate
Par Lorenzo DuBois Baber, John Hope Franklin, Charles P. Henry, Jonathan Scott Holloway, Ben Keppel, Beverly Lindsay, Princeton Lyman, Edwin Smith, Hanes Walton Jr.. 2007
Nobel Peace Prize winner Ralph Johnson Bunche (1904-71) was one of the twentieth century’s foremost diplomats and intellectuals. In the…
wake of centennial celebrations of his birth, leading scholars and diplomats assess Bunche’s historical importance and enduring impact on higher education, public policy, and international politics. Their essays reveal not only the breadth of Bunche’s influence, such as his United Nations work to broker peace during times of civil war in Africa, the Middle East, and Asia, but also the depth of his intellectual perspectives on race, civil rights, higher education, and international law. Probing his publications, speeches, and public policy initiatives, the volume offers telling insights into the critical roles of universities, public intellectuals, and diplomats in working together to find solutions to domestic and international problems through public and scholarly engagement. In this way, the volume highlights the very connections that Bunche exhibited as an academic, intellectual, and diplomat. Contributors include Lorenzo DuBois Baber, John Hope Franklin, Jonathan Scott Holloway, Charles P. Henry, Ben Keppel, Beverly Lindsay, Princeton Lyman, Edwin Smith, and Hanes Walton Jr.Forbes Burnham: The Life and Times of the Comrade Leader (Critical Caribbean Studies)
Par Linden F. Lewis. 2024
It is virtually impossible to understand the history of modern Guyana without understanding the role played by Forbes Burnham. As premier…
of British Guiana, he led the country to independence in 1966 and spent two decades as its head of state until his death in 1985. An intensely charismatic politician, Burnham helped steer a new course for the former colony, but he was also a quintessential strongman leader, venerated by some of his citizens yet feared and despised by others. Forbes Burnham: The Life and Times of the Comrade Leader is the first political biography of this complex and influential figure. It charts how the political party he founded, the People’s National Congress, combined nationalist rhetoric, socialist policies, and Pan-Africanist philosophies. It also explores how, in a country already deeply divided between the descendants of African slaves and Indian indentured servants, Burnham consolidated political power by intensifying ethnic polarizations. Drawing from historical archives as well as new interviews with the people who knew Burnham best, sociologist Linden F. Lewis examines how his dictatorial tendencies coexisted with his progressive convictions. Forbes Burnham is a compelling study of the nature of postcolonial leadership and its pitfalls.The Politics of Potential: Global Health and Gendered Futures in South Africa (Medical Anthropology)
Par Michelle Pentecost. 2024
The first one thousand days of human life, or the period between conception and age two, is one of the…
most pivotal periods of human development. Optimizing nutrition during this time not only prevents childhood malnutrition but also determines future health and potential. The Politics of Potential examines early life interventions in the first one thousand days of life in South Africa, drawing on fieldwork from international conferences, government offices, health-care facilities, and the everyday lives of fifteen women and their families in Cape Town. Michelle Pentecost explores various aspects of a politics of potential, a term that underlines the first one thousand days concept and its effects on clinical care and the lives of childbearing women in South Africa. Why was the First One Thousand Days project so readily adopted by South Africa and many other countries? Pentecost not only explores this question but also discusses the science of intergenerational transmissions of health, disease, and human capital and how this constitutes new forms of intergenerational responsibility. The women who are the target of first one thousdand days interventions are cast as both vulnerable and responsible for the health of future generations, such that, despite its history, intergenerational responsibility in South Africa remains entrenched in powerfully gendered and racialized ways.Now with a new, easy-to-read page design, Kaplan's Nursing School Entrance Exams Prep is a focused review of the HESI…
A2 and the Kaplan Nursing Admission Test—two major nursing school entrance assessments. Exam-specific practice, concise content review, and proven test-taking strategies will prepare you to face the first test of your nursing career with confidence.The Best ReviewFour sample practice tests: two for HESI A2, two for the Kaplan exam.Diagnostic test to identify the topics where you need the most reviewTest-specific icons showing which content to review for the Kaplan vs. the HESIScience chapters broken out by topic: anatomy & physiology, biology, organ systems, and chemistryGrammar and writing sections specifically geared to the Kaplan testQuick-reference resources with frequently used math formulas and commonly misspelled words to rememberExpert GuidanceKaplan's expert nursing faculty reviews and updates content regularlyPractical advice for the career-change nursing studentWe invented test prep—Kaplan (www.kaptest.com) has been helping students for 80 years, and our proven strategies have helped legions of students achieve their dreamsThis open access book is written by world-renowned experts on radiomolecular precision oncology to celebrate the work, life, principles and…
ideology of Richard P Baum.It includes commentaries, reviews and some thought provoking novel ideas on radionuclide precision oncology, covering topics such as various aspects of theranostics and molecular radiotherapy like radiolabeled peptides, radiolabeled antibodies, dosimetry, and quality control as well as the diagnosis and treatment of specific tumor types. Featuring contributions by biologists, physicists, chemists, mathematicians, geneticists, and physicians from a range of specialties, this Festschrift is highly interdisciplinary and will be a valuable resource for future precision oncologists.How the Boogeyman Became a Poet
Par Tony Keith Jr.. 2024
Poet, writer, and hip-hop educator Tony Keith Jr. makes his debut with a powerful YA memoir in verse, tracing his…
journey from being a closeted gay Black teen battling poverty, racism, and homophobia to becoming an openly gay first-generation college student who finds freedom in poetry. Perfect for fans of Elizabeth Acevedo, George M. Johnson, and Jacqueline Woodson.Tony dreams about life after high school, where his poetic voice can find freedom on the stage and page. But the Boogeyman has been following Tony since he was six years old. First, the Boogeyman was after his Blackness, but Tony has learned It knows more than that: Tony wants to be the first in his family to attend college, but there’s no path to follow. He also has feelings for boys, desires that don’t align with the script he thinks is set for him and his girlfriend, Blu.Despite a supportive network of family and friends, Tony doesn’t breathe a word to anyone about his feelings. As he grapples with his sexuality and moves from high school to college, he struggles with loneliness while finding solace in gay chat rooms and writing poetry. But how do you find your poetic voice when you are hiding the most important parts of yourself? And how do you escape the Boogeyman when it's lurking inside you?Marcus Aurelius: The Stoic Emperor (Ancient Lives)
Par Donald J. Robertson. 2019
Experience the world of Roman emperor Marcus Aurelius and the tremendous challenges he faced and overcame with the help of…
Stoic philosophy This novel biography brings Marcus Aurelius (121–180 CE) to life for a new generation of readers by exploring the emperor&’s fascinating psychological journey. Donald J. Robertson examines Marcus&’s relationships with key figures in his life, such as his mother, Domitia Lucilla, and the emperor Hadrian, as well as his Stoic tutors. He draws extensively on Marcus&’s own Meditations and correspondence, and he examines the emperor&’s actions as detailed in the Augustan History and other ancient texts. Marcus Aurelius struggled to reconcile his philosophy and moral values with the political pressures he faced as emperor at the height of Roman power. Robertson examines Marcus&’s attitude toward slavery and the moral dilemma posed by capturing enemies in warfare; his attitude toward women; the role of Stoicism in shaping his response to the threat of civil war; the treatment of Christians under his rule; and the naming of his notorious son Commodus as his successor. Throughout, the Meditations is used to shed light on the mind of the emperor—his character, values, and motives—as Robertson skillfully weaves together Marcus&’s inner journey as a philosopher with the outer events of his life as a Roman emperor.Bioremediation for Sustainable Environmental Cleanup
Par Anju Malik, Vinod Kumar Garg. 2024
The present book, Bioremediation for Sustainable Environmental Cleanup, has a compilation of seventeen chapters comprehensively describing the state-of-the-art on emerging…
bioremediation approaches employed for sustainable environmental clean-up of diverse environmental pollutants such as metal(loid)s, polycyclic aromatic hydrocarbons, dyes, pesticides, petroleum hydrocarbons, etc., by using bacteria, fungi, algae, higher plants, and novel materials like biohybrids, nano-biomaterials, and graphitic carbon nitride (g-C3N4). Different bioremediation strategies such as biosorption, bioprecipitation, bioaccumulation, biodegradation, biotransformation etc. have been described in detail. The emphasis throughout, however, is on sustainable environmental clean-up. Eminent researchers from various countries located in diverse geographical areas, including Argentina, Canada, Germany, India, Pakistan, South Africa, the United Kingdom, and the United States of America, have contributed towards the chapters of this book.Frederick Douglass: Narrative of the Life / My Bondage and My Freedom / Life and Times (Classic Bks.)
Par Frederick Douglass. 1994
Henry Louis Gates, Jr. presents the only authoritative edition of all three autobiographies by the escaped slave who became a great…
American leader.Here in this Library of America volume are collected Frederick Douglass's three autobiographical narratives, now recognized as classics of both American history and American literature. Writing with the eloquence and fierce intelligence that made him a brilliantly effective spokesman for the abolition of slavery and equal rights, Douglass shapes an inspiring vision of self-realization in the face of monumental odds.Narrative of the Life of Frederick Douglass, an American Slave (1845), published seven years after his escape, was written in part as a response to skeptics who refused to believe that so articulate an orator could ever have been a slave. A powerfully compressed account of the cruelty and oppression of the Maryland plantation culture into which Douglass was born, it brought him to the forefront of the anti-slavery movement and drew thousands, black and white, to the cause.In My Bondage and My Freedom (1855), Douglass expands the account of his slave years. With astonishing psychological penetration, he probes the painful ambiguities and subtly corrosive effects of black-white relations under slavery, and recounts his determined resistance to segregation in the North. The book also incorporates extracts from Douglass&’s speeches, including the searing &“What to the Slave Is the Fourth of July?&”Life and Times, first published in 1881, records Douglass&’s efforts to keep alive the struggle for racial equality udirng Reconstruction. John Brown, Abraham Lincoln, William Lloyd Garrison, and Harriet Beecher Stowe all feature prominently in this chronicle of a crucial epoch in American history. The revised edition of 1893, presented here, includes an account of his controversial diplomatic mission to Haiti.This volume contains a detailed chronology of Douglass&’s life, notes providing further background on the events and people mentioned, and an account of the textual history of each of the autobiographies.LIBRARY OF AMERICA is an independent nonprofit cultural organization founded in 1979 to preserve our nation&’s literary heritage by publishing, and keeping permanently in print, America&’s best and most significant writing. The Library of America series includes more than 300 volumes to date, authoritative editions that average 1,000 pages in length, feature cloth covers, sewn bindings, and ribbon markers, and are printed on premium acid-free paper that will last for centuries.Biological Motion: A History of Life
Par Janina Wellmann. 2024
A captivating exploration of the changing definitions of life in biologyBiological Motion studies the foundational relationship between motion and life.…
To answer the question, &“What is Life?,&” prize-winning historian of science Janina Wellmann engages in a transdisciplinary investigation of motion as the most profound definition of living existence.For decades, information and structure have dominated the historiography of the life sciences with its prevailing focus on DNA structure and function. Now more than ever, motion is a crucial theme of basic biological research. Tracing motion from Aristotle&’s animal soul to molecular motors, and from medical soft robotics to mathematical analysis, Wellmann locates biological motion at the intersection of knowledge domains and scientific and cultural practices. She offers signposts to mark the sites where researchers, technologies, ideas, and practices opened up new paths in the constitution of the phenomenon of motion. An ambitious rethinking of the life sciences, Biological Motion uncovers the secret life of movement and offers a new account of what it means to be alive.The Heart and Its Healing Plants: Traditional Herbal Remedies and Modern Heart Conditions
Par Wolf-Dieter Storl. 2009
An ethnobotanical look at ancient heart beliefs, heart-strengthening herbs, and folk remedies for cardiovascular diseases• Discusses traditional understandings of the…
heart from early European cultures and indigenous peoples of the Americas, Asia, and Africa • Examines the heart as the home of the soul and an organ of perception and looks at traditional beliefs on what makes the heart sick • Presents a materia medica of plants used for millennia to treat heart-related conditions as well as plants in use by modern herbalists and cardiologists Among our ancestors as well as indigenous people still maintaining traditional diets there is little record of heart diseases in the modern sense. In the traditional worldview, the heart was considered the home of the soul and the source of love and vitality. As such, heart sickness was not seen as a result of poor nutrition, too much stress, or lack of exercise, but reflected an imbalance of the heart&’s emotional and spiritual energies. Plants and folk remedies used as traditional heart medicine worked on the mental and spiritual level to help make the heart happy again. In this book, renowned ethnobotanist Wolf D. Storl, Ph.D., examines traditional understandings of the heart from early European cultures and indigenous peoples of the Americas, Asia, and Africa as well as a wealth of plants used in both ancient and contemporary times to treat heart conditions and ailments. He explores the heart as an organ of perception as well as its ability to remember, citing studies about the phenomenon of complete personality changes following a transplant. He examines what makes the heart sick, including different healing paradigms used to address the causes. He also looks at how time is perceived by the heart and how the modern epidemic of heart disease can be linked to our culture&’s pervasive disconnection from nature&’s rhythms. Presenting a materia medica of heart-strengthening herbs and folk remedies for cardiovascular diseases, the author offers in-depth descriptions of plants used for millennia to treat heart-related conditions as well as plants in use by modern herbalists and cardiologists. Sharing a holistic view of the heart—and heart disease—based on traditional perspectives, ethnomedical research, and herbal wisdom, this book reveals new ways to heal the heart by recognizing its integrated role in our physical, emotional, and spiritual wellness.Gute Kinderschutzverfahren: Tatsachenwissenschaftliche Grundlagen, rechtlicher Rahmen und Kooperation im familiengerichtlichen Verfahren
Par Jörg M. Fegert, Thomas Meysen, Heinz Kindler, Katrin Chauviré-Geib, Ulrike Hoffmann, Eva Schumann. 2023
In Kinderschutzfällen ist es Aufgabe der Jugendämter und Familiengerichte, im Raum stehende Kindeswohlgefährdungen einzuschätzen und gegebenenfalls durch geeignete Hilfen und…
Maßnahmen abzuwenden. Diese Einschätzungen und Entscheidungen können den weiteren Lebensweg von Kindern und ihren Eltern stark beeinträchtigen. Umso wichtiger ist es, dass die an familiengerichtlichen Kinderschutzverfahren beteiligten professionellen Akteure sich über ihre eigenen Aufgaben und die der anderen im Klaren sind, damit sie gut zusammenarbeiten können.Das vorliegende Buch vermittelt Grundlagenwissen aus verschiedenen Disziplinen und bietet damit das Fundament für eine gute interdisziplinäre Zusammenarbeit. Es enthält tatsachenwissenschaftliche Erkenntnisse zu Kindeswohlgefährdungen und deren Abwendung Grundlagenwissen zur kindlichen EntwicklungOrientierung zu den beteiligten Akteuren, Vernetzung und Interdisziplinarität Kenntnisse über die rechtlichen Rahmenbedingungen Grundzüge zum Ablauf von KinderschutzverfahrenDie Publikation orientiert sich am interdisziplinären Online-Kurs „Gute Kinderschutzverfahren“ (https://guteverfahren.elearning-kinderschutz.de/) und bietet allen juristischen, sozialpädagogischen, psychologischen und medizinischen Fachkräften die für qualifizierte Kinderschutzverfahren benötigten vertieften Grundlagenkenntnisse. Es handelt sich um eine Open-Access-Publikation mit freiem und uneingeschränktem Zugang zur elektronischen Ausgabe.How to Live Free in a Dangerous World: A Decolonial Memoir
Par Shayla Lawson. 2024
&“Phenomenal.... A memoir that opens into the world, with brilliance, courage, and elegant prose.... This is a book to read, read…
again, and remember.&”—Imani Perry, New York Times bestselling author of the National Book Award winner South to AmericaPoet and journalist Shayla Lawson follows their National Book Critics Circle finalist This Is Major with these daring and exquisitely crafted essays, where Lawson journeys across the globe, finds beauty in tumultuous times, and powerfully disrupts the constraints of race, gender, and disability.Named a Most Anticipated Book of 2024 by Elle, Them, Book Riot, LitHub, Stylecaster, and Chicago Review of Books In their new book, Shayla Lawson reveals how traveling can itself be a political act, when it can be a dangerous world to be Black, femme, nonbinary, and disabled. With their signature prose, at turns bold, muscular, and luminous, Shayla Lawson travels the world to explore deeper meanings held within love, time, and the self. Through encounters with a gorgeous gondolier in Venice, an ex-husband in the Netherlands, and a lost love on New Year&’s Eve in Mexico City, Lawson&’s travels bring unexpected wisdom about life in and out of love. They learn the strength of friendships and the dangers of beauty during a narrow escape in Egypt. They examine Blackness in post-dictatorship Zimbabwe, then take us on a secretive tour of Black freedom movements in Portugal. Through a deeply insightful journey, Lawson leads readers from a castle in France to a hula hoop competition in Jamaica to a traditional theater in Tokyo to a Prince concert in Minnesota and, finally, to finding liberation on a beach in Bermuda, exploring each location—and their deepest emotions—to the fullest. In the end, they discover how the trials of marriage, grief, and missed connections can lead to self-transformation and unimagined new freedoms.