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Articles 141 à 160 sur 2054
The Laboratory Zebrafish (Laboratory Animal Pocket Reference)
Par Claudia Harper, Christian Lawrence. 2011
Like other books in the Laboratory Animal Pocket Reference Series, this guide covers all aspects pertaining to the use of…
these organisms including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management. In the relatively brief spanDomestic Violence: Intervention, Prevention, Policies, and Solutions
Par Richard L. Davis. 2008
Domestic violence does not begin the day an adult heterosexual male decides to beat and batter an adult heterosexual female.…
Domestic violence is a complicated and multifaceted enigma that includes child, sibling, spousal, intimate partner, and elder abuse. Despite spending billions of dollars on domestic violence, the number of some categories ofHealthcare Data Analytics (Chapman & Hall/CRC Data Mining and Knowledge Discovery Series)
Par Chandan K. Reddy, Charu C. Aggarwal. 2015
At the intersection of computer science and healthcare, data analytics has emerged as a promising tool for solving problems across…
many healthcare-related disciplines. Supplying a comprehensive overview of recent healthcare analytics research, Healthcare Data Analytics provides a clear understanding of the analytical techniques currently availablePractical Radiological Anatomy
Par Sarah McWilliams. 2011
An illustrated and concise revision textbook, this book is designed for doctors training in radiology and preparing for the First…
FRCR exam. Using a convenient format arranged by body system, it contains high-quality images demonstrating the key features of basic anatomy. It supplies both conventional imaging and cross-sectional CT and MRI anatomy, presents guidelines on how to interpret images, includes case studies in each chapter, and discusses commonly encountered pitfalls. The text matches the current curriculum of the FRCA Part 1 and Part 2A exams.Advanced Organic Synthesis: A Laboratory Manual
Par Dmitry V. Liskin, Penny Chaloner. 2016
Laboratory experience equips students with techniques that are necessary for professional practice. Advanced Organic Synthesis: A Laboratory Manual focuses on…
a mechanistic background of key reactions in organic chemistry, gives insight into well-established trends, and introduces new developments in the field.The book features experiments performeGastrointestinal Eponymic Signs: Bedside Approach to the Physical Examination
Par Steven H. Yale, Halil Tekiner, Eileen S. Yale, Ryan C. Yale. 2023
This book provides a novel method to teach eponymically named physical signs of the alimentary tract and intrabdominal organs. The…
focus is on the historical aspect of the named signs, how to perform the sign described by the author, and the pathophysiologic mechanisms involved in eliciting a positive test. The goal is to guide the reader to appreciate how these bedside signs provide a more profound understanding of the mechanism of disease. By doing so, they become more than simply rote memorization but an appreciation of how a direct hands-on assessment involving observing, engaging, listening, and touching the patient assists in diagnosis. Hence, these techniques provided the additional benefit of better connecting the practitioner to the patients and maintaining the art of medicine, which is rapidly losing its foothold within the medical community. This book will serve as a teaching tool for learners, teachers, and practicing physicians to preserve the art of the physical examination using a form of a case-based teaching and learning style approach. Illustrations throughout the text provide a visual representation of how to perform the sign. The authors believe this method of teaching and learning is more meaningful to the student in that they will be able to associate the name with the person's historical features, the sign, and its pathophysiologic mechanism(s). Gastrointestinal Eponymic Signs is a must-have resource for medical students, residents, fellows, teaching faculty, and any practicing physician seeking to understand how physical examination signs assist in diagnosis.Transesophageal Echocardiography in Pediatric Congenital Cardiac Surgery and Catheter Intervention
Par Shen-Kou Tsai, Jou-Kou Wang, Shyh-Jye Chen. 2023
This book reviews the history and evolution of intraoperative transesophageal echocardiography (TEE) as applied in various pediatric congenital heart surgeries, catheter intervention procedures…
and hybrid surgeries. The development of the pediatric TEE is described, including safety and efficacy data in infants and neonates. Practical insights of the use of TEE in cardiac surgery and catheter intervention are highlighted through actual case presentations with images and illustrations. Topics covered include TEE monitoring from pre-procedural planning, real-time assist during the surgery, confirmation of the intended results, as well as identification of residual lesions that require further surgical correction. This book will be a valuable resource for practitioners working in the field of pediatric congenital heart diseases surgery and interventional procedures where TEE plays a vital role.Glutathione (Oxidative Stress and Disease #1)
Par Leopold Flohé. 2019
This is the first serious attempt to synthesize all that became known of glutathione over the last three decades. The…
book contains an update of glutathione biosynthesis with special emphasis on its regulation in adaptive stress responses. Other chapters review glutathione transport systems and glutathione peroxidases and their differences in substrate specificities and localization. Further contributions center on the diversified roles of different glutathione-S-transferases and the roles of nitrosoglutathione and glutaredoxins - a subfamily of redoxins. The book closes with discussions of the analogous or homologous thiol metabolism in pathogens and the potential suitability of involved enzymes as drug targets.Key selling features: Summarizing the way glutathione is involved in stress responses Compiling the multiple ways glutathione affects inflammatory responses Disclosing how glutathione dampens programmed cell death such as ferroptosis Exploring the enigma of how enzymes accelerate glutathione-dependent processes Discussing how detoxification and redox regulation is mediated by glutathionylation Reviewing the ways glutaredoxins catalyze protein disulfide reduction Highlighting the medical impact of glutathione-related metabolic pathways Illustrating the role thiol metabolism of pathogens might play in drug discoveryQuantification, Validation and Uncertainty in Analytical Sciences: An Analyst's Companion
Par Max Feinberg, Serge Rudaz. 2024
Quantification, Validation and Uncertainty in Analytical Sciences Companion guide explaining all processes in measuring uncertainty in quantitative analytical results Quantification,…
Validation and Uncertainty in Analytical Sciences provides basic and expert knowledge by building on the sequence of operations starting from the quantification in analytical sciences by defining the analyte and linking it to the calibration function. Proposing a comprehensive approach to MU (Measurement Uncertainty) estimation, it empowers the reader to apply Method Accuracy Profile (MAP) efficiently as a statistical tool in measuring uncertainty. The text elucidates several examples and template worksheets explaining the theoretical aspects of the procedure and includes novel method validation procedures that can accurately estimate the data obtained in measurements. It also enables the reader to provide practical insights to improve decision making by accurately evaluating and comparing different analytical methods. Brings together an interdisciplinary approach with statistical tools and algorithms applied in analytical chemistry and written by two international experts with long-standing experience in the field of Analytical measurements and Uncertainty, Quantification, Validation and Uncertainty in Analytical Sciences includes information on: The know-how of methods in an analytical laboratory, effective usage of a spurious measurement and methods to estimate errors. Quantification, calibration, precision, trueness, MAP addons, estimating MU for analytical sciences, and uncertainty functionsEmploying measurement uncertainty, sampling uncertainty, quantification limits, and sample conformity assessmentDecision making, uncertainty and standard addition method, and accuracy profile for method comparison Quantification, Validation and Uncertainty in Analytical Sciences is an ideal resource for every individual quantifying or studying analytes. With several chapters dedicated to MU’s practical use in decision making demonstrating its advantages, the book is primarily intended for professional analysts, although researchers and students will also find it of interest.Orthopaedic Knowledge Update®: Sports Medicine 6 brings together the most relevant literature and the latest research from the past 5…
years. More than 150 top-notch contributors collaborated on this succinct review of pertinent advances in sports medicine. Find brand-new content on hip instability and microinstability, return-to-play criteria following anterior cruciate ligament injury, exercise-induced bronchorestriction, development of emergency action plans, and imaging of the foot and ankle.Langman's Medical Embryology
Par T. W. Sadler. 2024
Concise, clearly written, and vibrantly illustrated, Langman’s Medical Embryology, 15th Edition, makes complex embryology concepts approachable to help you build…
the clinical understanding essential to your success in medical practice, nursing, or other health professions. Hundreds of full-color illustrations clarify the stages of embryonic development with rich detail, and engaging learning features, clinical examples, and online review questions ready you for the challenges ahead on your exams and in clinical practice.The little-known stories of the people responsible for what we know today as modern medical ethics.In Making Modern Medical Ethics,…
Robert Baker tells the counter history of the birth of bioethics, bringing to the fore the stories of the dissenters and whistleblowers who challenged the establishment. Drawing on his earlier work on moral revolutions and the history of medical ethics, Robert Baker traces the history of modern medical ethics and its bioethical turn to the moral insurrections incited by the many unsung dissenters and whistleblowers: African American civil rights leaders, Jewish Americans harboring Holocaust memories, feminists, women, and Anglo-American physicians and healthcare professionals who were veterans of the World Wars, the Cold War, and the Vietnam War.The standard narrative for bioethics typically emphasizes the morally disruptive medical technologies of the latter part of the twentieth century, such as the dialysis machine, the electroencephalograph, and the ventilator, as they created the need to reconsider traditional notions of medical ethics. Baker, however, tells a fresh narrative, one that has historically been neglected (e.g., the story of the medical veterans who founded an international medical organization to rescue medicine and biomedical research from the scandal of Nazi medicine), and also reveals the penalties that moral change agents paid (e.g., the stubborn bureaucrat who was demoted for her insistence on requiring and enforcing research subjects&’ informed consent). Analyzing major statements of modern medical ethics from the 1946–1947 Nuremberg Doctors Trials and Nuremberg Code to A Patient&’s Bill of Rights, Making Modern Medical Ethics is a winning history of just how respect and autonomy for patients and research subjects came to be codified.Head Over Heels: A Love Affair in Words and Pictures
Par Melissa Newman. 2023
An invitation to the private world of Joanne Woodward and Paul Newman, one of America&’s most iconic couples, in a…
lavishly illustrated oversize photo book affectionately curated by their daughter Melissa Newman. Their love story is the stuff of Hollywood legend. Joanne Woodward and Paul Newman became not only movie stars and stage actors, but also artistic collaborators, political activists, and philanthropists whose legacies are expansive and enduringly modern. This visually immersive oversize book chronicles their romance through the photographs of an impressive list of contributors, including: Richard Avedon Sid Avery Ralph Crane Bruce Davidson John Engstead Leo Fuchs Milton H. Greene Philippe Halsman John R. Hamilton Leonard McCombe Gordon Parks Sanford Roth Roy Schatt Lawrence Schiller Sam Shaw Bradley Smith Stewart Stern David Sutton These striking images—many rare and some never before published—are accompanied by snapshots, letters, handwritten notes, and family treasures. Together they beautifully illuminate the connection between two complex, passionate artists who opened their hearts and minds to each other for over half a century. This book is an homage to the possibility and power of love.Scattershot: Life, Music, Elton, and Me
Par Bernie Taupin. 2023
**NEW YORK TIMES BESTSELLER** An evocative, clear-eyed, and revealing memoir by Bernie Taupin, the lyrical master and long-time collaborator of…
Elton John&“I loved writing, I loved chronicling life and every moment I was cogent, sober, or blitzed, I was forever feeding off my surroundings, making copious notes as ammunition for future compositions. . . . The thing is good, bad, or indifferent I never stopped writing, it was as addictive as any drug.&” This is the memoir music fans have been waiting for. Half of one of the greatest creative partnerships in popular music, Bernie Taupin is the man who wrote the lyrics for Elton John, who conceived the ideas that spawned countless hits, and sold millions and millions of records. Together, they were a duo, a unit, an immovable object. Their extraordinary, half-century-and-counting creative relationship has been chronicled in biopics (like 2019's Rocketman) and even John's own autobiography, Me. But Taupin, a famously private person, has kept his own account of their adventures close to his chest, until now. Written with honesty and candor, Scattershot allows the reader to witness events unfolding from Taupin's singular perspective, sometimes front and center, sometimes from the edge, yet always described vibrantly, with an infectious energy that only a vivid songwriter's prose could offer. From his childhood in the East Midlands of England whose imagination was sparked and forever informed by the distinctly American mythopoetics of country music and cowboy culture, to the glittering, star-studded fishbowl of &’70s and &’80s Beverly Hills, Scattershot is simultaneously a Tom Jones-like picaresque journey across a landscape of unforgettable characters, as well as a striking, first-hand account of a creative era like no other and one man&’s experience at the core of it. An exciting, multi-decade whirlwind told in a non-linear yet grounded narrative, Scattershot whizzes around the world as we ride shotgun with Bernie on his extraordinary life. We visit Los Angeles with him and Elton on the cusp of global fame. We spend time with him in Australia almost in residency at an infamous rock 'n' roll hotel in an endless blizzard of drugs. And we spend late, late night hours with John Lennon, with Bob Marley, and hanging with Frank Sinatra. And beyond the world of popular music, we witness memorable encounters with writers like Graham Greene, painters like Andy Warhol and Salvador Dali, and scores of notable misfits, miscreants, eccentrics, and geniuses, known and unknown. Even if they're not famous in their own right, they are stars on the page, and we discover how they inspired the indelible lyrics to songs such as &“Tiny Dancer,&” &“Candle in the Wind,&” &“Bennie and The Jets,&” and so many more. Unique and utterly compelling, Scattershot will transport the reader across the decades and around the globe, along the way meeting some of the greatest creative minds of the 20th century, and into the vivid imaginings of one of music's most legendary lyricists.60 Songs That Explain the '90s
Par Rob Harvilla. 2023
NAMED A BEST MUSIC BOOK OF 2023 by PITCHFORK, VARIETY, AND ROLLING STONE A companion to the #1 music podcast on Spotify, this…
book takes readers through the greatest hits that define a weirdly undefinable decade. The 1990s were a chaotic and gritty and utterly magical time for music, a confounding barrage of genres and lifestyles and superstars, from grunge to hip-hop, from sumptuous R&B to rambunctious ska-punk, from Axl to Kurt to Missy to Santana to Tupac to Britney. In 60 SONGS THAT EXPLAIN THE '90s, Ringer music critic Rob Harvilla reimagines all the earwormy, iconic hits Gen Xers pine for with vivid historical storytelling, sharp critical analysis, rampant loopiness, and wryly personal ruminations on the most bizarre, joyous, and inescapable songs from a decade we both regret entirely and miss desperately.Breaking Through Depression: A Guide to the Next Generation of Promising Research and Revolutionary New Treatments
Par Philip William Gold. 2023
&“A thorough, up-to-date, and upbeat introduction to current scientific thinking about mood disorders and their treatment. An important resource for…
patients and their families—and for anyone curious about progress in psychiatric research."―Peter D. Kramer, Listening to ProzacThis inspiring exploration of the recent advances in depression research and treatment shares new methods that offer promising paths to wellness. Breaking Through Depression explores how the anatomy of the brain and the biochemistry of nerve impulses play a major role in how we view ourselves and the world. Drawing from his long-term research, Dr. Philip W. Gold makes the case for depression arising at the intersection of genetic vulnerability with stressful, disturbing life experiences that get encoded in our emotional memory. Breaking Through Depression will delve into the interplay between our anatomy and our lived experiences as the key to understanding why there are such individual differences in how we make connections with others, deal with adversity, or recover from trauma. More importantly, Dr. Gold reveals the latest breakthroughs that can heal people struggling with depression, including: The FDA has fast-tracked Psilocybin and Ketamine as anti-depressant treatments, which cause immediate improvement in depressive symptoms. Low-energy lasers have been developed that can stimulate these areas directly and painlessly to relieve symptoms in treatment-resistant patients suffering from major depression. Scientists are developing genetically &‘thumbprinted' antidepressants that can be individually tailored to match a person's DNA increasing their effectiveness. Inflammation in the body and the brain is a prominent component of depressive illness, to the point that anti-inflammatory agents are useful in the treatment of depression. Incredible progress with gene therapy including a treatment overcoming the BDNF gene mutation that interferes with resiliency, promotes vulnerability to depression, and inhibits the capacity of antidepressants to work effectively. These are just a few of the fascinating new developments explored in Breaking Through Depression and the many reasons for hope that Dr. Gold shares in this groundbreaking book.Leslie F*cking Jones
Par Leslie Jones. 2023
A NEW YORK TIMES BESTSELLER A BARNES AND NOBLE'S BEST BOOKS OF THE YEAR A TOWN & COUNTRY BEST CELEBRITY MEMOIR OF 2023…
A VULTURE BEST COMEDY BOOK OF 2023 Hey you guys, it&’s Leslie. I&’m excited to share my story with you. Now, I&’m gonna be honest: Some of the details might be vague because a b*tch is fifty-five and she&’s smoked a ton of weed. But while bits might be a touch hazy, I can promise you the underlying truth is REAL. Whether I&’m talking about my childhood growing up in the South, my early stand-up days driving from gig to gig through the darkest parts of our country and praying I wouldn&’t get murdered, what Chris Rock told Lorne Michaels, that time I wanted to shoot Whoopi Goldberg on SNL, and yeah, I&’ll tell you all about Ghostbusters and the nudes and Supermarket Sweep and The Daily Show . . . I&’m sharing it all in these pages. It&’s not easy being a woman in comedy, especially when you&’re a tall-*ss Black woman with a trumpet voice. I have to fight so that no one takes me for granted, and no one takes advantage. These are the stories that explain why. (Cue the Law & Order theme.)Well at Work: Creating Wellbeing in any Workspace
Par Esther M. Sternberg. 2023
LONGLISTED FOR THE 2023 OWL AWARDS Full of science-backed tips on how to design any workspace for physical and emotional…
wellbeing, &“Well at Work helps us thrive wherever we work.&” (Arianna Huffington) Whether you work in a traditional office or a corner of your bedroom, staying well at work need not be a luxury. But wellness at work isn&’t just about staying physically healthy; it&’s also about reducing stress and improving mood, focus, energy, and productivity.Well at Work reveals how to optimize our workspaces for wellbeing across the seven domains of integrative health: stress and resilience, movement, sleep, relationships, environment, nutrition, and spirituality, and even the air we breathe. You&’ll learn: How the environment you work in all day can affect your sleep at night Optimal lighting and noise levels for reducing stress and improving focus How to adjust temperature and humidity to stay alert and protect against infection Why open-plan offices can keep you more active The myriad benefits of access to nature (and how to bring nature indoors) Office layouts that foster social interactions but not distraction Foods to enhance cognitive performance And more Along the way, you&’ll meet the scientists and doctors, designers and architects, and building science professionals who are striving to make workplaces more conducive to wellbeing. And you&’ll glimpse into the future of the workplace, where artificial intelligence and the metaverse will help us create environments that respond to our individual needs. Above all, you&’ll come away with a menu of simple, &“innovative, and often overlooked&” (Dr. Richard Carmona) steps anyone can take to be—and stay—well at work.Steven Spielberg All the Films: The Story Behind Every Movie, Episode, and Short
Par Arnaud Devillard, Olivier Bousquet, Nicolas Schaller. 2023
A first-of-its-kind deep dive into Steven Spielberg's decades-long career, covering everything from early short films and television episodes to each of…
his more than 30 feature length-films. Organized chronologically and covering every short film, television episode, and blockbuster movie that Steven Spielberg has ever directed, Steven Spielberg All the Films draws upon years of research to tell the behind-the-scenes stories of how each project was conceived, cast, and produced; from the creation of the costumes to the search for perfect locations; details about Spielberg's work with longtime collaborators like George Lucas, producer Kathleen Kennedy, and composer John Williams; and of course, the direction of some of Hollywood's most memorable scenes. Spanning more than fifty years, this book details the creative processes that resulted in numerous classic films like E.T. the Extra-Terrestrial, Jaws, Jurassic Park, The Color Purple, Schindler's List, and Saving Private Ryan (to name just a few). Newer work like Lincoln, The Post, and The Fabelmans is also featured alongside awards stats, original release dates, box office totals, casting details, and other insider scoops that will keep fans turning pages. Celebrating one of cinema's most iconic artists, Steven Spielberg All the Films is the authoritative guide to the man who invented the Hollywood blockbuster.Radiotheranostics - A Primer for Medical Physicists I: Physics, Chemistry, Biology and Clinical Applications (ISSN)
Par Cari Borrás, Michael G. Stabin. 2024
This book covers scientific, clinical, and educational aspects of radiotheranostics in cancer control. Setting the framework, the first volume defines…
radiotheranostics and describes the history of radionuclide therapy and theranostics, and the biology of cancer. It examines the clinical applications of unconjugated radionuclides, such as ¹³¹I and ²²³Ra, and of radionuclide-conjugated cancer-specific vectors: peptides, small molecules, antibodies, and nanoparticles; introduces clinical trials and drug development; and reviews epidemiological studies and the adverse effects of radionuclide therapy – both radiation injuries and chemical toxicity. It presents the chemistry and physics of radionuclide production, discusses radioactivity measurements and traceability, and addresses important instrumentation aspects: calibration, quantitative imaging, and quality control. Volume I concludes with guidance on the education, training, and competence of a radiotheranostic multidisciplinary team and summarizes the principal physics characteristics of theranostics today – including many to be expanded in the second volume – while offering a glimpse into tomorrow. This volume provides the foundations for the more advanced second volume, which explores dosimetric and radiation safety, aiming to empower medical physicists and demonstrate to the cancer community how to improve cancer control and yield increased patient survival times.It will be a valuable reference for medical and health physicists with basic knowledge of nuclear medicine.Key Features• Provides a comprehensive introduction to the topic, presenting readers with thorough treatment in a cohesive two-volume book.• Presents a rigorous approach while remaining accessible to students and trainees in the field.• Contains consistent and extensive references to allow readers to delve deeper into the subject.