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Eddie Olczyk: Beating the Odds in Hockey and in Life
Par Eddie Olczyk, Perry Lefko. 2019
Eddie Olczyk had built a life and career most people could only dream of. Growing up in the suburbs of…
Chicago, he fell in love with the game of hockey during an era when most kids preferred balls to pucks. Against all odds, he played on the 1984 U.S. Olympic hockey team as a 17-year-old, and four months later he was drafted in the first round by his hometown Chicago Blackhawks. During an illustrious 16-year career, he played for and alongside some of the greatest franchises and players in history, winning a Stanley Cup with the unforgettable 1994 New York Rangers. Years later, he coached former teammate Mario Lemieux and Sidney Crosby on the Pittsburgh Penguins before transitioning into the broadcast booth, where he has become one of the most recognizable voices of the sport. He then combined his skills as an analyst with his second passion— horse racing—and became an integral part of NBC’s coverage of thoroughbreds. Away from the spotlight, Olczyk and his wife of three decades raised four adoring children. He was respected and admired by fans, friends, and peers. Life was sweet. Then, at 7:07 pm on August 4, 2017, his entire world turned upside down. In Eddie Olczyk: Beating the Odds in Hockey and in Life, one of the biggest names in American hockey has written an inspiring and entertaining memoir of his life both on and off the ice. From shooting hundreds of tennis balls at a goal in his childhood living room to the ups and downs of his improbable hockey career to rollicking stories from the booth and the backstretch, Olczyk guides readers on his journey toward his ultimate test: a battle against Stage 3 colon cancer. For years, Olczyk’s goal was to be the best husband, father, broadcaster, and handicapper he could be. Today he has a new one: to bring as much awareness and support to those fighting cancer as he possibly can. In this emotional but often hilarious autobiography, you’ll learn why the people who know Eddie Olczyk best might describe him as “tremendously tremendous.”Advanced Robotic Spine Surgery: A case-based approach
Par Michael Y. Wang, Steele III, William J., Timur Urakov. 2021
Robotic spine surgery is one of the fastest growing segments of the spine surgery market. Surgeons specialising in spine surgery…
are highly motivated to learn and improve their understanding of the indications,application,and future clinical scope of using new technological platforms. Spinal surgeons face time pressures but are hungry for new ways to effectively treat patients. This book presents information in the case study format. By using examples of surgical cases of an advanced nature (e.g. spinal deformity, minimally invasive surgery, combinatorial technology using the robot) this will differ from other texts. Each case study is written by a well-respected expert in the field and represents that surgeon’s most monumental case. Each case contains a concise patient history with indications, contraindications and insights to help the reader assimilate expert knowledge. The case studies examine both the unique and technical aspects of robotic planning and surgical execution, and include seminal bullet point sections: Key take away points; Tips and pearls to avoid pitfalls; and "how I could have done this better.” This new text provides valuable and practical knowledge for spine surgeons and others involved in robotic surgery.Adolescence, Discrimination, and the Law: Addressing Dramatic Shifts in Equality Jurisprudence
Par Roger J.R. Levesque. 2015
Explores the shifts and the research used to support civil rights claims of discrimination, particularly relating to minority youths’ rights…
to equal treatment In the wake of the civil rights movement, the legal system dramatically changed its response to discrimination based on race, gender, and other characteristics. It is now showing signs of yet another dramatic shift, as it moves from considering difference to focusing on neutrality. Rather than seeking to counter subjugation through special protections for groups that have been historically (and currently) disadvantaged, the Court now adopts a “colorblind” approach. Equality now means treating everyone the same way. This book explores these shifts and the research used to support civil rights claims, particularly relating to minority youths’ rights to equal treatment. It integrates developmental theory with work on legal equality and discrimination, showing both how the legal system can benefit from new research on development and how the legal system itself can work to address invidious discrimination given its significant influence on adolescents—especially those who are racial minorities—at a key stage in their developmental life. Adolescents, Discrimination, and the Law articulates the need to address discrimination by recognizing and enlisting the law’s inculcative powers in multiple sites subject to legal regulation, ranging from families, schools, health and justice systems to religious and community groups. The legal system may champion ideals of neutrality in the goals it sets itself for treating individuals, but it cannot remain neutral in the values it supports and imparts. This volume shows that despite the shift to a focus on neutrality, the Court can and should effectively foster values supporting equality, especially among youth.Macrolides as Immunomodulatory Agents (Progress in Inflammation Research #92)
Par Bruce K. Rubin, Masaharu Shinkai. 2024
For over 50 years, clinicians have known that macrolide antibiotics have effects on inflammation and the immune system that are…
not related to their antimicrobial properties. These immunomodulatory properties, best described for treating inflammatory airway diseases, protect the lung and the host and improve clinical status. This book summarizes our current knowledge regarding proposed mechanisms for these properties, established clinical results, and what the future may hold with emphasis on novel clinical applications and the fascinating development of non-antimicrobial macrolides with preserved and enhanced immunomodulatory properties.Breast Cancer Research and Treatment: Innovative Concepts (Cancer Treatment and Research #188)
Par Ouissam Al Jarroudi, Khalid El Bairi, Giuseppe Curigliano. 2023
This book focuses on innovative treatment options for breast cancer, including surgery, radiotherapy, systemic therapy and of course immunotherapy that…
is changing outcomes in some aggressive breast cancer histotypes. Subsequent chapters also address the ongoing emerging research in the screening, diagnostics, and management of all subtypes of breast cancers. All current landscapes and future perspectives in each molecular subtype: luminal, HER2-positive, and triple-negative breast cancers are discussed within the different chapters.Breast cancer is still the most common cancer and cause of cancer deaths among women worldwide. The improvement of breast cancer outcome appears to be strictly related to the validation of precise biomarkers that enable us to better select personalized approaches in breast cancer management.The closing chapters deal with the challenges of conducting research in the era of precision medicine for cancer. The book is edited and authored by leading experts in this field and will be of interest for clinicians and scientists alike.Medicinal Plants and Antimicrobial Therapies
Par Vinay Kumar, Varsha Shriram, Abhijit Dey. 2024
This book serves as an excellent comprehensive material covering the current understandings and updates on antimicrobial resistance (AMR) and the…
use of medicinal plant resources for tackling it. Chapters cover important aspects of AMR and strategies to address this threatening issue with medicinal plants and their resources. One health perspectives for addressing AMR have been presented for the readers. Antimicrobial medicinal plant therapeutic resources including crude extracts, active fractions, pure molecules and essential oils, besides using them as functionalizing agents for nano-antimicrobials have been covered. Further, plant endophytes as a source of antimicrobial compounds have been discussed. Chapters cover both the bactericidal as well as resistance-reversal (or potentiating/ combinatorial therapies) potencies of medicinal plant resources. The book also focuses on how medicinal plant resources effectively target major determinants of AMR. Use of metabolomics in understanding and targeting AMR mechanisms and identifying potent phyto-therapeutics has been discussed as well. The book is a valuable read for both experienced and younger researchers working in the field of AMR and related fields in biomedicine, pharmacy, and clinical research.Univentricular Congenital Heart Defects and the Fontan Circulation: Practical Manual for Patient Management
Par Paul Clift, Konstantinos Dimopoulos, Annalisa Angelini. 2023
This book provides a concise, practically applicable guide to the management of patients born with a univentricular heart defect. It…
describes the anatomy and epidemiology of the univentricular heart, while guidance is provided on how to manage both fetal and neonatal patients with this defect, as well as those in later childhood and adulthood. The utilization of the Fontan operation for patients with a univentricular heart is described in detail. Management of early and late Fontan failure is also discussed, and the pregnant patient is also described, enabling the reader to develop a deep understanding of how to manage these patients in their daily practice. Univentricular Congenital Heart Defects: Practical Manual for Patient Management comprehensively reviews the management of univentricular heart defects and the use of Fontan-type surgery. It is a valuable resource for the experienced practitioner seeking a manual on the latest available techniques and for trainees who want to develop a thorough understanding of how to manage patients with these congenital heart defects.The Philosophy of Criminal Law: An Introduction
Par Christopher Cowley, Nicola Padfield. 2024
The Philosophy of Criminal Law: An Introduction explores the central concepts of criminal law, such as intention, complicity and duress, and…
how they work, both within criminal law practice and in our everyday lives, from legal and philosophical perspectives. At the heart of the book is the central philosophical concept of responsibility: what does it mean to be responsible for an act, to hold someone responsible for an act, or to give an excuse in order to avoid responsibility for an act? Offering talking points to enrich an ongoing conversation, this unique textbook addresses all of these questions in an accessible way for law and non-law students alike. Real cases are examined in detail and a critical approach to the criminal law is adopted throughout. The focus will be mainly on the criminal law of England and Wales, with occasional cases from other jurisdictions, and occasional examples from other areas of law. This text will be ideal reading for advanced undergraduate and graduate students of law, philosophy and criminology, as well as political science and sociology.Handbook of Cerebrovascular Disease and Neurointerventional Technique (Contemporary Medical Imaging)
Par Mark R. Harrigan, John P. Deveikis. 2023
This fourth edition offers a practical guide to endovascular treatment of cerebrovascular disease and provides a comprehensive reference for the…
related neurovascular anatomy and the various disorders that affect the vascular system. Chapters cover fundamental principles underlying cerebral and spinal angiography; interventional techniques, devices, and practice guidelines; and commonly encountered cerebrovascular disorders for which interventional and endovascular methods are appropriateBuilding on the previous edition, the text is presented similarly in style and scope to emphasize accessibility and ease of reading. All chapters are fully updated to include more recent data, and obsolete products and techniques are replaced with the most current technology. Some key updates include:A greater emphasis on the use of radial artery access for the discussed endovascular techniques.The associations of COVID-19 with ischemic stroke and the implications of providing care for cerebrovascular patients during a pandemic.An extensive update to the acute ischemic stroke chapter with new references and format to more closely follow the format of other chapters in that section.Expansion of the pediatric sections of disease chapters, including discussions of genetic associations with disease. This is an ideal guide for clinicians and trainees in neurology, neurosurgery and neuroradiology, as well as practicing clinicians in related fields caring for patients with cerebrovascular disease.Blockchain in Healthcare: Analysis, Design and Implementation (Future of Business and Finance)
Par Chang Lu, Mohan Tanniru. 2023
This books brings readers a holistic understanding of blockchain adoption in healthcare by not only considering the technical fundamentals of…
use cases, but also the regulatory, informational and organizational challenges and solutions. The book also provides frameworks and toolkits to manage the entire life cycle of adoption, including analysing the environment and feasibility, application design from a user-centred perspective, and implementation strategies that would overcome organizational and informational barriers. Specific issues addressed include but are not limited to: How to analyse the value propositions in healthcare and which distributed actors should be engaged to fulfil these propositions? What policies and practices need to be reviewed to ensure security and privacy of the information shared? How to design blockchain systems that seamlessly integrate with other stakeholder applications, while only the needed information is in the distributed architecture? How can blockchain implementation be managed from governance and risk mitigation perspectives, especially when multiple actors are involved?By reading this book, blockchain enthusiasts, health informatics professionals and healthcare executives will be better prepared to leverage the transformative potential of blockchain for healthcare.Medical Decision Making
Par Harold C. Sox, Michael C. Higgins, Douglas K. Owens, Gillian Sanders Schmidler. 2024
MEDICAL DECISION MAKING Detailed resource showing how to best make medical decisions while incorporating clinical practice guidelines and decision support…
systems Sir William Osler, a legendary physician of an earlier era, once said, “Medicine is a science of uncertainty and an art of probability.” In Osler’s day, and now, decisions about treatment often cannot wait until the diagnosis is certain. Medical Decision Making is about how to make the best possible decision given that uncertainty. The book shows how to tailor decisions under uncertainty to achieve the best outcome based on published evidence, features of a patient’s illness, and the patient’s preferences. Medical Decision Making describes a powerful framework for helping clinicians and their patients reach decisions that lead to outcomes that the patient prefers. That framework contains the key principles of patient-centered decision-making in clinical practice. Since the first edition of Medical Decision Making in 1988, the authors have focused on explaining key concepts and illustrating them with clinical examples. For the Third Edition, every chapter has been revised and updated. Written by four distinguished and highly qualified authors, Medical Decision Making includes information on: How to consider the possible causes of a patient’s illness and decide on the probability of the most important diagnoses. How to measure the accuracy of a diagnostic test. How to help patients express their concerns about the risks that they face and how an illness may affect their lives. How to describe uncertainty about how an illness may change over time. How to construct and analyze decision trees. How to identify the threshold for doing a test or starting treatment How to apply these concepts to the design of practice guidelines and medical policy making. Medical Decision Making is a valuable resource for clinicians, medical trainees, and students of decision analysis who wish to fully understand and apply the principles of decision making to clinical practice.ACSM's Resources for the Group Exercise Instructor
Par American College of Sports Medicine. 2023
ACSM’s Resources for the Group Exercise Instructor, 2nd Edition, equips fitness professionals with the knowledge and the skills needed to…
effectively lead group exercise in gyms, studios, recreational facilities, and clubs. An essential resource for undergraduate exercise science programs, students in pre-professional programs, and those independently prepping for the ACSM-GEI certification, this engaging, accessible text reflects the authoritative expertise of the American College of Sports Medicine (ACSM) and delivers complete preparation for becoming an ACSM Certified Group Exercise Instructor. The extensively revised and reorganized 2nd Edition streamlines learning and aligns content to the domains of the ACSM Certified Group Exercise Instructor Exam, boosting exam confidence and delivering step-by-step guidance to ensure success in professional practice.In 2018, the members of the African Union adopted the African Continental Free Trade Area Agreement (AfCFTA). This book examines…
the AfCFTA, dissecting its key provisions. It stresses the importance of the AfCFTA in the context of increasing episodes of trade protection in Africa, and it theorizes on the role of the treaty organs. The book also examines the importance of citizen participation for the success of the AfCFTA, as well as exploring the role sub-state actors can play. Ultimately, the study adds to the understanding of the array of problems that are associated with regional trade in Africa and the role law plays in resolving these problems. It will be of importance to academics and students of international law, especially those with an interest in African trade law, as well as legal professionals and policymakers.Toxicology of Fishes
Par Kristine L. Willett, Neelakanteswar Aluru. 2024
This up-to-date, comprehensive toxicology handbook is devoted to the effects of environmental pollution on fish. Fish species represent nearly half…
of all vertebrates and have become important sentinels for environmental contamination and model organisms for understanding adverse outcomes from exposures. This new edition is written by recognized experts, and it highlights the significant research progress in fish toxicology that has resulted from rapid technological developments in analytical, biochemical, and genomic sciences. The book: Discusses fundamental topics such as toxicokinetics in fishes, processes governing biotransformation within these organisms, and reactive oxygen species and oxidative stress. Explains key target organ systems for chemical impacts in fish, such as the nervous and immune systems, and how fishes can develop resistance to chemical toxicity. Covers multi-transgenerational effects on fishes, epigenetics, proteomics and metabolomics, and adverse outcome pathways. Replacing the case studies in the first edition, this update delves into the impacts of microplastics, pharmaceuticals, and oil spills in dedicated final chapters. With nearly 200 illustrations and tables, this comprehensive reference work presents concepts in a way that is useful for both novices to and experts in the field of fish toxicology.The Future of Alzheimer's: Finding Inspiration & Hope Through Expert Insight
Par Sharon Ricardi. 2023
A collection of informative and inspirational thoughts of many of the nation&’s leaders in research, medicine, education, senior care and…
advocacy around the subject of Alzheimer&’s disease.The Future of Alzheimer's features candid views from experts on how they respond today to someone on the difficult journey of Alzheimer&’s and what they believe is the future hope for a cure.More than 20 experts in the field of Alzheimer's research or caretakers are asked two key questions:What advice would you give to the loved ones of someone who is newly diagnosed?Do you think there will be a cure, and if so, when?Their answers help provide context and hope for patients, caretakers and loved ones looking for answers by providing helpful insights on the disease and what's to come.Alzheimer's prevalence in the US makes it the 6th leading cause of death, killing more than half a million people, mainly seniors, every year and experts believe this number will only grow. The Future of Alzheimer's seeks to make this and other forms of dementia less of the devastating diagnosis it is now for all of those people.An evidence-based guide for doctors diagnosing, testing, and treating children with PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Strep infections).In…
the early 1990s, a group of researchers at the National Institute of Mental Health began collecting data on children who had developed neuropsychiatric disorders (OCD and tics) following infections. They found evidence that antineuronal antibodies had developed in some of these children which attacked the basal ganglia region of the brain. MRI and PET scans in these children demonstrated inflammatory changes in the basal ganglia as well. In 1997, the researchers published the first article to describe this syndrome that they named PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Strep infections). In PANDAS, an autoimmune attack on the brain occurs following a Strep infection. PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) is a broader term that also includes cases following exposure to other infections, toxins, and even stress. Clinicians treating children with PANS and PANDAS have found that antibiotics targeted at the offending organisms, steroids, and IVIG results in marked improvement and occasionally complete remission of the neuropsychiatric symptoms. Disturbing symptoms consistent with many DSM-5 psychiatric disorders manifest in patients with PANS and PANDAS—yet we know that there is a biologic basis for the changes in these children. As a result, these disorders require us, as physicians, to view mental illness in an entirely new way. Resistance to this change in paradigm has made PANS and PANDAS difficult for clinicians to diagnose, unbearable for parents to endure, and controversial for scholars to accept. As such, there is no recognized standard of care. We have written this work in an effort to change that. This is a textbook by physicians for physicians. It was written to bring back some of the art of medicine to physicians caring for a group of children and families who really need it. PANS and PANDAS are complex disorders that demand a rich, multifaceted response with novel treatment approaches. The material in this book is assembled from the peer-reviewed medical literature, in combination with over thirty years of clinical experience caring for the sickest patients, both in and out of the hospital. Here you will find conclusive evidence for the existence and pathophysiology of PANS and PANDAS, alongside testing and treatment interventions the author has successfully used in his own practice with hundreds of children. The book concludes with rich appendices including commonly used labs, doses of medications and supplements, a sample flare protocol, extensive support for parents, sample IVIG orders, and much more. We hope this resource allows you, the physician, to help these suffering families heal.Law, Humans and Plants in the Andes-Amazon: The Lawness of Life (Law, Justice and Ecology)
Par Iván Darío Vargas Roncancio. 2024
Extending law beyond the human, the book examines the conceptual openings, methodological challenges, and ethical conundrums of law in a…
time of socio-ecological transition. How do we learn and practice law across epistemic and ontological difference? What sort of methodologies do we need? In what sense does conjuring other-than-human beings as sentient, cognitive and social agents—rather than mere recipients of state-sanctioned rights—transform what we mean by law and rights of nature in Latin America and beyond? Legal institutions exclusively focused on human perspectives seem insufficiently capable of addressing current socio-ecological challenges in Latin America and beyond. In response, this book strives to integrate other-than-human beings within legal thinking, institutions, and decision-making protocols. Weaving together various fields of knowledge and worldmaking practices that include – but are not limited to – Indigenous legal traditions, ecological law, multispecies ethnography, and ecological economics, the book pursues a multi-sited ethnography that focuses on the entanglement of law, ecology, and Indigenous cosmologies in Southern Colombia. In so doing, it articulates a general post-anthropocentric legal theory which is proposed, a tool to address socio-ecological challenges such as climate change and bio-cultural loss. This book will be of interest to scholars and students in the disciplines of environmental law, Earth law and ecological law, legal theory and critical legal studies; as well as others working in the in the fields of Indigenous studies, environmental humanities, legal anthropology, and sustainability and climate change justice.Cancer screening has been carried out for six decades – however, there are many unsolved problems: how to estimate key parameters…
involved in screenings, such as sensitivity, the time duration in the preclinical state (i.e., sojourn time), and time duration in the disease-free state; how to estimate the distribution of lead time, the diagnosis time advanced by screening; how to evaluate the long-term outcomes of screening, including the probability of overdiagnosis among the screen-detected; when to schedule the first exam based on one’s current age and risk tolerance; and when to schedule the upcoming exam based on one’s screening history, age, and risk tolerance. These problems need proper probability models and statistical methods in order to be dealt with. Features: This book gives a concise account of the analysis of cancer screening data, using probability models and statistical methods. Real data sets are provided so that cancer researchers and statisticians can apply the methods in the learning process. It develops statistical methods in the commonly used disease progressive model. It provides solutions to practical problems and introduces open problems. It provides a framework for the most recent developments based on the author’s research. The book is primarily aimed at researchers and practitioners from biostatistics and cancer research. Readers should have the prerequisite knowledge of calculus, probability, and statistical inference. The book could be used as a one-semester textbook on the topic of cancer screening methodology for a graduate-level course.Impeachment in a Global Context: Law, Politics, and Comparative Practice (Routledge Frontiers in Accountability Studies)
Par Chris Monaghan, Matthew Flinders, Aziz Z. Huq. 2024
This volume considers the use of impeachment within a global context. The book brings together leading scholars and experts to…
give an insight into significant periods in the development of impeachment and its modern comparative use. Divided into five parts, the opening chapter introduces the topic and underlines its significance in terms of understanding the relationship and inter-dependence among politics, governance and the law. It also offers a novel conceptual framework that facilitates the global mapping of impeachment processes. Part I presents a thematic approach that explores the topic of impeachment through the lenses of democracy, human rights and the rule of law. With these themes in mind, Part II focuses on those parts of the world where impeachment is generally recognised as a core constitutional process including the United States, South Korea, Brazil and other countries in South America. Part III continues with the process of constitutional mapping by moving to a focus on those countries where impeachment is arguably an important but largely secondary or peripheral process. This includes chapters on Denmark, Iceland, Sri Lanka and the Philippines and flows through into Part IV’s focus on areas of the world where impeachment matters and may even be increasing in terms of visibility but, for a number of reasons, arguably exists within a satellite status in terms of constitutional processes and safeguards. The fifth and final section steps back in an attempt to assess impeachment processes from a broad comparative perspective. The collection presents the definitive text on impeachment for students and scholars with an interest in comparative public law, politics and constitutional studies.This book contrasts and compares the different application of the law relating to the welfare interests and rights of children…
in France and Germany. It does so by applying the same matrix of indicators to explore jurisdictional differences between welfare interests and rights in the contexts of public family law (civil – care and protection etc and criminal – youth justice etc); private family law (matrimonial, adoption etc); and hybrid public/private family law (wardship, adoption from state care etc). By profiling the nations in accordance with the same indicators it reveals important jurisdictional differences in the extent to which welfare interests or rights determine how the law is currently applied to children in France and Germany. This volume will be of interest to academics and researchers engaged in law, legal studies and social policy, and also to policymakers, administrators, and professionals working within child welfare systems.