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Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis
Par Robert A. Copeland. 2023
ENZYMES A complete and approachable introduction to the study of enzymes, from theory to practice Enzymes catalyze the bulk of…
important biological processes, both metabolic and biochemical. They are specialized proteins whose function is determined by their structure, understanding which is therefore a key focus of biological, pharmacological, and agrarian research, among many others. A thorough knowledge of enzyme structure, pathways, and mechanisms is a fundamental building block of the life sciences and all others connected to them. Enzymes offers a detailed introduction to this critical subject. It analyzes enzyme proteins at the structural level and details the mechanisms by which they perform their catalyzing functions. The book’s in-depth engagement with primary literature and up-to-date research allows it to continuously deploy illustrative examples and connect readers with further research on key subjects. Fully updated after decades as the standard text, this book unlocks a thriving field of biological and biochemical research. Readers of the third edition of Enzymes will also find: Expanded chapters on steady-state and transient-state enzyme kinetics, structural components of enzymes, and more New chapters on enzyme regulation, enzyme-macromolecule interactions, enzyme evolution, and enzymes in human health Key Learning Points at the beginning of each chapter to assist students and instructors Enzymes promises to continue as the standard reference on this subject for practitioners of the life sciences and related fields in both academia and industry.The Disabled Body in Contemporary Art
Par Ann Millett-Gallant. 2024
The second edition offers an essential update to the foundational first edition, The Disabled Body in Contemporary Art. Featuring updated chapters…
and case studies, this second edition will not only expand on the first edition but will bring a new focus to contemporary disabled artists and their embodied, multimedia work.Essential Clinical Global Health (Essentials)
Par Brett D. Nelson. 2015
Essential Clinical Global Health is a brand-new, pioneering, and evidence-based textbook that provides a clinical overview of the increasingly prominent…
specialty of global health. Originally developed from a course at Harvard Medical School, and now with contributions from nearly 100 world-renowned global health experts from across the globe, this textbook presents vital information required of students, trainees, and clinicians during their international experiences and training. Essential Clinical Global Health introduces readers to the up-to-date knowledge, skills, and approaches needed for productive and rewarding global health experiences. It provides essential clinical information on the diagnosis, management, and prevention of the leading causes of morbidity and mortality in low- and middle-income countries. The textbook also includes practical guidance on topics such as health systems, population-based approaches, cultural awareness and sensitivity, travel preparedness and safety, and career development in global health. With key learning objectives in each chapter, practical clinical advice, setting-appropriate guidelines, personal field experiences from student and clinician contributors, Essential Clinical Global Health is the first global health textbook with a clinical focus for healthcare students, trainees, and providers.A companion website at www.wileyessential.com/globalhealth features self-assessment questions and videos.Herz-Kreislauf (Springer-Lehrbuch)
Par Thomas F. Lüscher, Ulf Landmesser. 2024
Der Blick aufs GanzeEs ist immer wieder dasselbe: Wenn im klinischen Abschnitt endlich die spannenden Krankheitsbilder kommen, sind Anatomie und…
Physiologie längst vergessen. Mühsam muss man alles wiederholen, um zu verstehen, worum es bei der Erkrankung geht.Lernen Sie ein Organsystem doch einfach „am Stück“: von der Anatomie über die Physiologie bis zur Diagnostik und Therapie von Erkrankungen. Dieses Buch ist ideal für das Lernen im Modul, hier verstehen Sie das Organsystem im Zusammenhang. Die Erkrankungen des Herz-Kreislauf-Systems werden systematisch abgehandelt - endlich genügt ein einziges Buch, um den ganzen Themenblock durchzuarbeiten. Und dabei helfen Ihnen: Praktische Anleitungen für Diagnostik und TherapieZahlreiche diagnostische BilderNeueste Erkenntnisse und TherapieverfahrenMerksätze, Tabellen und Übersichten mit den wichtigsten FaktenWegen seiner Praxisnähe ist dieser Band sowohl für Medizinstudenten als auch für Ärzte in der kardiologischen Aus- und Weiterbildung bestens geeignet.Für die dritte Auflage wurde das Buch sorgfältig aktualisiert und um zwei neue Kapitel zur pulmonalen Hypertonie sowie Erkrankungen des venösen Systems ergänzt. So bleiben Sie auch mit der dritten Auflage am Puls der Zeit in der Kardiologie!Understanding Mental Health Apps: An Applied Psychosocial Perspective (Palgrave Studies in Cyberpsychology)
Par Lewis Goodings, Darren Ellis, Ian Tucker. 2024
This is the first book to look exclusively from at the use of MHapps from an applied psychosocial perspective. Much of…
the academic literature on MHapps in psychology focuses on the clinical efficacy of using apps (e.g., depression reduction as result of using a certain app) and will typically report on the use of randomised controlled trials (or a similar method) to illustrate the use of apps as a tool for improving a psychological condition. Therefore, the main benefit of this book is that it recognises the impact of apps from a social perspective and will aim to show how everyday forms of distress are embedded in the use of these apps and the broader set of relations that constitute people’s everyday lives. The content of this book will identify how an applied social perspective can offer insight into the power of apps to shape our sense of ourselves and of others. This book will be of use to educators and students in psychology, sociology, health studies, media studies andcultural studies.Surgery of Craniosynostosis and Related Midface Deformities: An Atlas and Step-by-Step Guide
Par Michael Rasse. 2024
This atlas offers a comprehensive overview of osteotomies performed on the calvaria and midface for both syndromic and non-syndromic craniosynostosis.It…
presents a systematic approach, beginning with calvarial osteotomies. The author introduces a general type of osteotomy that can be applied for total vault remodeling in cases of total synostosis. These osteotomies can also be modified and used in single or combined synostoses. To shape the calvaria, the book describes the use of metal plates as a scaphold. These plates can be prebent on 3-D models and used to fix the segments after osteotomies. Following that, resorbable osteosynthesis is performed, and the metal plates are subsequently removed. This unique approach, combined with standardized osteotomies, ensures highly predictable results that are not currently described in textbooks. The book includes clinical examples for each type of synostosis and various combinations, including two-stage procedures and combinations with distraction techniques. These examples provide surgeons with a solid foundation for addressing different cases. In the chapter on midface osteotomies, the book explains the access and technique for performing the LeFort-III osteotomy using cadaver and clinical figures. It covers all types of LeFort-I to III osteotomies and their combinations through clinical cases. The book illustrates the osteotomies, osteosynthesis, distraction techniques, and combinations using clinical examples. Additionally, the book demonstrates the method of computer planning, the fabrication of osteotomy guides, and the use of preformed plates to define the position of the segments.The book's primary objective is to serve as a surgical guide that transcends the boundaries of medical specialties. Given that this type of surgery is often performed by different specialists across institutions and countries, the book aims to facilitate cooperation and provide a practical application tool for surgeons beyond offering a clinical overview.Subjected to 22 hours of interrogation, torture and beating by South African police on September 6, 1977, Steve Biko died…
six days later. Donald Woods, Biko's close friend and a leading white South African newspaper editor, exposed the murder helping to ignite the black revolution.The Balance Within: The Science Connecting Health and Emotions
Par Esther M. Sternberg. 2001
A thrilling scientific detective story, The Balance Within tells how researchers finally uncovered the elusive mind-body connection and what it…
means for our health. Since ancient times humans have felt intuitively that emotions and health are linked, and recently there has been much popular speculation about this notion. But until now, without compelling evidence, it has been impossible to say for sure that such a connection really exists and especially how it works. Now, that evidence has been discovered.In this beautifully written book, Dr. Esther Sternberg, whose discoveries were pivotal in helping to solve this mystery, provides first hand accounts of the breakthrough experiments that revealed the physical mechanisms - the nerves, cells, and hormones - used by the brain and immune system to communicate with each other. She describes just how stress can make us more susceptible to all types of illnesses, and how the immune system can alter our moods. Finally, she explains how our understanding of these connections in scientific terms is helping to answer such crucial questions as "Does stress make you sick?" "Is a positive outlook the key to better health?" and "How do our personal relationships, work, and other aspects of our lives affect our health?"A fascinating, elegantly written portrait of this rapidly emerging field with enormous potential for finding new ways to treat disease and cope with stress, The Balance Within is essential reading for anyone interested in making their body and mind whole again.Not Even My Name: A True Story
Par Thea Halo. 2001
A riveting account of exile from Turkish genocide, brought to light for the first time ever in Sano Halo's personal…
story Not Even My Name exposes the genocide carried out during and after WW I in Turkey, which brought to a tragic end the 3000-year history of the Pontic Greeks (named for the Pontic Mountain range below the Black Sea). During this time, almost 2 million Pontic Greeks and Armenians were slaughtered and millions of others were exiled. Not Even My Name is the unforgettable story of Sano Halo's survival, as told to her daughter, Thea, and of their trip to Turkey in search of Sano's home 70 years after her exile. Sano Halo was a 10-year-old girl when she was torn from her ancient, pastoral way of life in the mountains and sent on a death march that annihilated her family. Stripped of everything she had ever held dear, even her name, Sano was sold by her surrogate family into marriage when still a child to a man three times her age. Not Even My Name follows Sano's marriage, the raising of her ten children in New York City, and her transformation as an innocent girl who was forced to move from a bucolic life to the 20th century in one bold stride. Written in haunting and eloquent prose, Not Even My Name weaves a seamless texture of individual and group memory, evoking all the suspense and drama of the best told tales.24: Life Stories and Lessons from the Say Hey Kid
Par Willie Mays, John Shea. 1951
THE INSTANT NEW YORK TIMES BESTSELLER ANDSAN FRANCISCO CHRONICLE BESTSELLERThe legendary Willie Mays shares the inspirations and influences responsible for…
guiding him on and off the field in this reflective and inspirational memoir."Even if, like me, you thought you had pretty much read and heard all there was to read and hear about Willie Mays, this warmhearted book will inform and reward you. And besides, what true baseball fan can ever get enough of Willie Mays? Say Hey! Read on and enjoy." —From the Foreword by Bob Costas “It’s because of giants like Willie that someone like me could even think about running for President.” —President Barack ObamaWidely regarded as the greatest all-around player in baseball history because of his unparalleled hitting, defense and baserunning, the beloved Willie Mays offers people of all ages his lifetime of experience meeting challenges with positivity, integrity and triumph in 24: Life Stories and Lessons from the Say Hey Kid.Presented in 24 chapters to correspond with his universally recognized uniform number, Willie’s memoir provides more than the story of his role in America’s pastime. This is the story of a man who values family and community, engages in charitable causes especially involving children and follows a philosophy that encourages hope, hard work and the fulfillment of dreams.“I was very lucky when I was a child. My family took care of me and made sure I was in early at night. I didn’t get in trouble. My father made sure that I didn’t do the wrong thing. I’ve always had a special place in my heart for children and their well-being, and John Shea and I got the idea that we should do something for the kids and the fathers and the mothers, and that’s why this book is being published. We want to reach out to all generations and backgrounds. Hopefully, these stories and lessons will inspire people in a positive way.” —Willie MaysIndia Calling: An Intimate Portrait of a Nation's Remaking
Par Anand Giridharadas. 2012
Reversing his parents' immigrant path, a young American-born writer returns to India and discovers an old country making itself newAnand…
Giridharadas sensed something was afoot as his plane from America prepared to land in Bombay. An elderly passenger looked at him and said, "We're all trying to go that way," pointing to the rear. "You, you're going this way?"Giridharadas was returning to the land of his ancestors, amid an unlikely economic boom. But he was interested less in its gold rush than in its cultural upheaval, as a new generation has sought to reconcile old traditions and customs with new ambitions and dreams.In India Calling, Giridharadas brings to life the people and the dilemmas of India today, through the prism of his émigré family history and his childhood memories of India. He introduces us to entrepreneurs, radicals, industrialists, and religious seekers, but, most of all, to Indian families. He shows how parents and children, husbands and wives, cousins and siblings are reinventing relationships, bending the meaning of Indianness, and enduring the pangs of the old birthing the new. Through their stories, and his own, he paints an intimate portrait of a country becoming modern while striving to remain itself.The Silver Swan: In Search of Doris Duke
Par Sallie Bingham. 2020
"Men who inherit great wealth are respected, but women who do the same are ridiculed. In The Silver Swan, Sallie…
Bingham rescues Doris Duke from this gendered prison and shows us just how brave, rebellious, and creative this unique woman really was, and how her generosity benefits us to this day.” —Gloria Steinem A bold portrait of Doris Duke, the defiant and notorious tobacco heiress who was perhaps the greatest modern woman philanthropistIn The Silver Swan, Sallie Bingham chronicles one of the great underexplored lives of the twentieth century and the very archetype of the modern woman. “Don’t touch that girl, she’ll burn your fingers,” FBI director J. Edgar Hoover once said about Doris Duke, the inheritor of James Buchanan Duke’s billion-dollar tobacco fortune. During her lifetime, she would be blamed for scorching many, including her mother and various ex-lovers. She established her first foundation when she was twenty-one; cultivated friendships with the likes of Jackie Kennedy, Imelda Marcos, and Michael Jackson; flaunted interracial relationships; and adopted a thirty-two year-old woman she believed to be the reincarnation of her deceased daughter. This is also the story of the great houses she inhabited, including the classically proportioned limestone mansion on Fifth Avenue, the sprawling Duke Farms in New Jersey, the Gilded Age mansion Rough Point in Newport, Shangri La in Honolulu, and Falcon’s Lair overlooking Beverly Hills. Even though Duke was the subject of constant scrutiny, little beyond the tabloid accounts of her behavior has been publicly known. In 2012, when eight hundred linear feet of her personal papers were made available, Sallie Bingham set out to probe her identity. She found an alluring woman whose life was forged in the Jazz Age, who was not only an early war correspondent but also an environmentalist, a surfer, a collector of Islamic art, a savvy businesswoman who tripled her father’s fortune, and a major philanthropist with wide-ranging passions from dance to historic preservation to human rights. In The Silver Swan, Bingham is especially interested in dissecting the stereotypes that have defined Duke’s story while also confronting the disturbing questions that cleave to her legacy.And Then Life Happens: A Memoir
Par Auma Obama. 2012
A moving account by Auma Obama about her life in Africa and Europe, and her relationship with her brother, Barack…
Obama.While her younger brother Barack grew up in the U.S. and Indonesia, Auma Obama's childhood played out at the other end of the world in a remote village in Kenya, the birthplace of the siblings' shared father. Barack and Auma met for the first time in the 1980s, and they built a lasting relationship which lead to travels together in Kenya, research into their family history and finally Auma's support for her brother's political career and eventual bid for the U.S. presidency.Auma spent sixteen years studying and living in Germany, moved to England for love, and gave birth to a daughter there. The tension between her original and chosen worlds and cultures was a constant challenge, and eventually Auma returned to Africa and worked to support young men and women in shaping their futures. In And Then Life Happens, her candid and emotional memoir, Auma shares her own story as well as recollections of and experiences with her famous brother, who says about their first encounter: "I hugged her, we looked at each other, and laughed. I knew right then that I loved her."Both a history of fine jewelry coming out of Paris in the Golden Age and a tour through the secretive…
world of high-end, privately-sold jewelry, Diving for Starfish is a stylish detective story with a glittering piece of jewelry at its heart. In the mid 1930s, in the workroom of the famous Parisian jeweler Boivin, a young jewelry designer named Juliette Moutard created one of the most coveted pieces of jewelry in the world—the famous starfish pin—still sought after today by aficionados of fine jewelry. The starfish, created out of gold and encrusted with 71 cabochon rubies and 241 small amethysts, was distinctive because its five rays were articulated, meaning that they could curl and conform to the bustline or shoulder of the women who wore it. The House of Boivin made three of them. Two of the women who bought and wore the starfish were Claudette Colbert and Millicent Rogers. Obsessed with the pin after she saw it in the private showroom of a Manhattan jewelry merchant, Cherie Burns set off on a journey to find out all she could about the elusive pins and the women who owned them. Her search took her around the world to Paris, London, New York, and Hollywood. Diving for Starfish is the story of these marvelous pieces of jewelry and the equally dazzling women who loved them.Knee Surgery: The Essential Step-by-Step Guide to Total Knee Recovery
Par Daniel Fulham O'Neill. 2009
In this age of same-day surgery and do-it-yourself health, Knee Surgery presents an easy-to-do, well-illustrated program of movement for knee…
rehabilitation - with a special focus on the mind/body connection - and describes the physical and mental rehabilitation process in complete detail, providing all the guidance you need to decrease pain and increase fitness after knee surgery. Millions of people have knee surgery each year, and in the years to come millions more will head to the O.R. Chances are, you or someone you know has had or will undergo knee surgery. Busy doctors, therapists, and athletic trainers have limited time to spend on quality physical and mental rehabilitation education, yet this is the key to full recovery.Written by renowned knee surgeon and Sport Psychologist Daniel F. O'Neill, M.D., Ed.D., this comprehensive and accessible guide presents what you'll want and need the most after knee surgery: a scientifically-based recovery program you can understand that will get you back to work and sports as quickly as possible.The Excruciating History of Dentistry: Toothsome Tales & Oral Oddities from Babylon to Braces
Par James Wynbrandt. 1998
For those on both sides of the dreaded dentist's chair, James Wynbrandt has written a witty, colorful, and richly informative…
history of the art and science of dentistry. To all of those dental patients whose whine rises in tandem with that of the drill, take note: You would do well to stifle your terror and instead offer thanks to Apollonia, the patron saint of toothache sufferers, that you face only fleeting discomfort rather than the disfiguring distress, or slow agonizing death oft meted out by dental-care providers of the past. The transition from yesterday's ignorance, misapprehension, and superstition to the enlightened and nerve-deadened protocols of today has been a long, slow, and very painful process.For example, did you know that: *Among the toothache remedies favored by Pierre Fauchard, the father of dentistry, was rinsing the mouth liberally with one's own urine.*George Washington never had wooden teeth. However, his chronic dental problems may have impacted the outcome of the American Revolution. *Soldiers in the Civil War needed at least two opposing front teeth to rip open powder envelopes. Some men called up for induction had their front teeth extracted to avoid service. *Teeth were harvested from as many as fifty thousand corpses after the Battle of Waterloo, a huge crop later used for dentures and transplants that became known as "Waterloo Teeth."The Matter of the Heart: A History of the Heart in Eleven Operations
Par Thomas Morris. 2017
An eye-opening and heroic story of pioneering heart surgeons, structured around eleven operations.For thousands of years the human heart remained…
the deepest of mysteries; both home to the soul and an organ too complex to touch, let alone operate on. Then, in the late nineteenth century, medics began going where no one had dared go before. The following decades saw the mysteries of the heart exposed, thanks to pioneering surgeons, brave patients and even sacrificial dogs. In eleven landmark operations, Thomas Morris tells us stories of triumph, reckless bravery, swaggering arrogance, jealousy and rivalry, and incredible ingenuity: the trail-blazing ‘blue baby’ procedure that transformed wheezing infants into pink, healthy children; the first human heart transplant, which made headline news around the globe. And yet the heart still feels sacred: just before the operation to fit one of the first artificial hearts, the patient’s wife asked the surgeon if he would still be able to love her.The Matter of the Heart gives us a view over the surgeon’s shoulder, showing us the heart’s inner workings and failings. It describes both a human story and a history of risk-taking that has ultimately saved millions of lives.Staying Strong: 365 Days a Year
Par Demi Lovato. 2013
Demi Lovato wakes up each morning and affirms her commitment to herself—to her health, her happiness, her being. Those commitments…
are the bedrock of her recovery and her work helping other young people dealing with the issues she lives with every single day. Demi is a platinum-selling recording artist whose latest album—DEMI—is already a smash hit. She's about to embark on her second season as a judge on X-Factor, and just launched The Lovato Treatment Scholarship Program. And she is an outspoken advocate for young people everywhere. Demi is also a young woman finding her way in the world. She has dealt deftly with her struggles in the face of public scrutiny, and she has always relied, not just on friends and family, but daily affirmations of her self-worth and value. Affirmations that steady her days and strengthen her resolve. Those affirmations have grown into STAYING STRONG, a powerful 365-day collection of Demi's most powerful, honest, and hopeful insights. Each day will provide the readers with a quote, a personal reflection and a goal. These are Demi's words. Words she lives by and shares with the people she loves and total strangers alike. They are a powerful testament to a young woman standing up and fighting back.Spirit of Adventure: Eagle Scouts and the Making of America's Future
Par Alvin Townley. 2009
An extraordinary journey alongside America's new generation of Eagle Scouts, who are discovering their purpose and bringing the values of…
Scouting to the world.Over the past century, Scouts have helped to guide the course of American history. But what does Scouting and the Eagle badge mean to the Scouts of today? How will they shape the future of Scouting and America itself? In Spirit of Adventure, Scouting expert and Eagle Scout Alvin Townley finds the answer.Townley traveled across the country and to the far corners of the globe to meet these young Eagle Scouts. He found them everywhere, continuing the life of adventure and service that they had begun in Scouting. He discovered them in Afghanistan providing medical care to villagers, in Australia saving coral reefs, at the Super Bowl and Olympic venues striving for victory, on desert cliffs and at inner-city schools teaching new lessons, in Africa bringing hope to children, and on the windswept deck of the aircraft carrier USS Nimitz preparing for takeoff.Whether doctors, activists, servicemen, entrepreneurs, or teachers, these young men are changing the world through bold actions that capture the essence of the Scouting tradition. In Spirit of Adventure, Townley answers important questions about the future of Scouting and America, while revealing stories of service, courage, and pure excitement that introduce our nation to an inspiring new generation of leaders.Firefight: The Century-Long Battle to Integrate New York's Bravest
Par Ginger Adams Otis. 2015
In 1919, when Wesley Williams became a New York City firefighter, he stepped into a world that was 100% white…
and predominantly Irish. As far as this city knew, black men in the Fire Department of New York (FDNY) tended horses.Nearly a century later, many things in the FDNY had changed—but not the scarcity of blacks. New York had about 300 black firefighters—roughly 3 percent of the 11,000 New York firefighters in a city of two million African Americans. That made the FDNY a true aberration compared to all the other uniformed departments, like the NYPD. Decades earlier, women and blacks had sued over its hiring practices and won. But the FDNY never took permanent steps to eradicate the inequities, which led to a courtroom show-down between New York City's billionaire Mayor, Mike Bloomberg, and a determined group of black activist firefighters. It was not until 2014 that the city settled the $98 million lawsuit.At the center of this book are stories of courage—about firefighters risking their lives in the line of duty but also risking their livelihood by battling an unjust system. Among them: FDNY Captain Paul Washington, a second generation black firefighter, who spent his multi-decade career fighting to get minorities on the job. He faced an insular culture made up of relatives who never saw their own inclusion as favoritism.Based on author Ginger Adams Otis' years of on the ground reporting, Firefight is an exciting blend of the high-octane energy of firefighting and critical Civil Rights history.